PDB entry 1oiq

View 1oiq on RCSB PDB site
Description: imidazopyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation
Class: kinase
Keywords: kinase, protein kinase, transferase, serine/threonine-protein kinase, ATP-binding, cell cycle, cell division, mitosis, phosphorylation,
Deposited on 2003-06-24, released 2003-09-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: 0.229
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1OIQ
    • Uniprot P24941 (0-297)
    Domains in SCOPe 2.07: d1oiqa_
  • Heterogens: HDU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1oiqA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1oiqA (A:)
    menfqkvekiggvvykarnkltgevvalkkitaireisllkelnhpnivklldvihtlyl
    vfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpqnllinte
    gaikladfgltlwyrapeillgckyystavdiwslgcifaemvtrralfpgdseidqlfr
    ifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkr
    isakaalahpffqdvtkpvphlrl