PDB entry 1ofq

View 1ofq on RCSB PDB site
Description: crystal structure of the tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from saccharomyces cerevisiae in complex with manganese(II)
Class: lyase
Keywords: beta-alpha-barrel, lyase, aromatic amino-acid biosynthesis synthase, aldolase, synthetase, manganese
Deposited on 2003-04-17, released 2004-04-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.221
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: SACCHAROMYCES CEREVISIAE [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ofqa_
  • Chain 'B':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: SACCHAROMYCES CEREVISIAE [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ofqb_
  • Chain 'C':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: SACCHAROMYCES CEREVISIAE [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ofqc_
  • Chain 'D':
    Compound: phospho-2-dehydro-3-deoxyheptonate aldolase
    Species: SACCHAROMYCES CEREVISIAE [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1ofqd_
  • Heterogens: MN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1ofqA (A:)
    msespmfaangmpkvnqgaeedvrilgydplaspallqvqipatptsletakrgrreaid
    iitgkddrvlvivgpcsihdleaaqeyalrlkklsdelkgdlsiimraylekprttvgwk
    glindpdvnntfninkglqsarqlfvnltniglpigsemldtispqyladlvsfgaigar
    ttesqlhrelasglsfpvgfkngtdgtlnvavdacqaaahshhfmgvtkhgvaaitttkg
    nehcfvilrggkkgtnydaksvaeakaqlpagsnglmidyshgnsnkdfrnqpkvndvvc
    eqiangenaitgvmiesninegnqgipaegkaglkygvsitdacigwettedvlrklaaa
    vrqrrevnkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ofqA (A:)
    vrilgydplaspallqvqipatptsletakrgrreaidiitgkddrvlvivgpcsihdle
    aaqeyalrlkklsdelkgdlsiimraylekpvgwkglindpdvnntfninkglqsarqlf
    vnltniglpigsemldtispqyladlvsfgaigarttesqlhrelasglsfpvgfkngtd
    gtlnvavdacqaaahshhfmgvthgvaaitttkgnehcfvilrggkkgtnydaksvaeak
    aqlpagsnglmidyshgnsnkdfrnqpkvndvvceqiangenaitgvmiesninegnqgi
    paegkaglkygvsitdacigwettedvlrklaaavrqrrevnk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1ofqB (B:)
    msespmfaangmpkvnqgaeedvrilgydplaspallqvqipatptsletakrgrreaid
    iitgkddrvlvivgpcsihdleaaqeyalrlkklsdelkgdlsiimraylekprttvgwk
    glindpdvnntfninkglqsarqlfvnltniglpigsemldtispqyladlvsfgaigar
    ttesqlhrelasglsfpvgfkngtdgtlnvavdacqaaahshhfmgvtkhgvaaitttkg
    nehcfvilrggkkgtnydaksvaeakaqlpagsnglmidyshgnsnkdfrnqpkvndvvc
    eqiangenaitgvmiesninegnqgipaegkaglkygvsitdacigwettedvlrklaaa
    vrqrrevnkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ofqB (B:)
    vrilgydplaspallqvqipatptsletakrgrreaidiitgkddrvlvivgpcsihdle
    aaqeyalrlkklsdelkgdlsiimrayleprttwkglindpdvnntfninkglqsarqlf
    vnltniglpigsemldtispqyladlvsfgaigarttesqlhrelasglsfpvgfkngtd
    gtlnvavdacqaaahshhfmgvtkhgvaaitttkgnehcfvilrggkkgtnydaksvaea
    kaqlpagsnglmidyshgnsnkdfrnqpkvndvvceqiangenaitgvmiesninegnqg
    iegkaglkygvsitdacigwettedvlrklaaavrqrrevnkk
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1ofqC (C:)
    msespmfaangmpkvnqgaeedvrilgydplaspallqvqipatptsletakrgrreaid
    iitgkddrvlvivgpcsihdleaaqeyalrlkklsdelkgdlsiimraylekprttvgwk
    glindpdvnntfninkglqsarqlfvnltniglpigsemldtispqyladlvsfgaigar
    ttesqlhrelasglsfpvgfkngtdgtlnvavdacqaaahshhfmgvtkhgvaaitttkg
    nehcfvilrggkkgtnydaksvaeakaqlpagsnglmidyshgnsnkdfrnqpkvndvvc
    eqiangenaitgvmiesninegnqgipaegkaglkygvsitdacigwettedvlrklaaa
    vrqrrevnkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ofqC (C:)
    vrilgydplaspallqvqipatptsletakrgrreaidiitgkddrvlvivgpcsihdle
    aaqeyalrlkklsdelkgdlsiimraylekprvgwkglindpdvnntfninkglqsarql
    fvnltniglpigsemldtispqyladlvsfgaigarttesqlhrelasglsfpvgfkngt
    dgtlnvavdacqaaahshhfmgvthgvaaitttkgnehcfvilrggkkgtnydaksvaea
    kaqlpagsnglmidyshgnsnkdfrnqpkvndvvceqiangenaitgvmiesninegnqg
    ipaegkaglkygvsitdacigwettedvlrklaaavrqrrevnk
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1ofqD (D:)
    msespmfaangmpkvnqgaeedvrilgydplaspallqvqipatptsletakrgrreaid
    iitgkddrvlvivgpcsihdleaaqeyalrlkklsdelkgdlsiimraylekprttvgwk
    glindpdvnntfninkglqsarqlfvnltniglpigsemldtispqyladlvsfgaigar
    ttesqlhrelasglsfpvgfkngtdgtlnvavdacqaaahshhfmgvtkhgvaaitttkg
    nehcfvilrggkkgtnydaksvaeakaqlpagsnglmidyshgnsnkdfrnqpkvndvvc
    eqiangenaitgvmiesninegnqgipaegkaglkygvsitdacigwettedvlrklaaa
    vrqrrevnkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ofqD (D:)
    vrilgydplaspallqvqipatptsletakrgrreaidiitgkddrvlvivgpcsihdle
    aaqeyalrlkklsdelkgdlsiimrayleprttvgwkglindpdvnntfninkglqsarq
    lfvnltniglpigsemldtispqyladlvsfgaigarttesqlhrelasglsfpvgfkng
    tdgtlnvavdacqaaahshhfmgvtkhgvaaitttkgnehcfvilrggkkgtnydaksva
    eakaqlpagsnglmidyshgnsnkdfrnqpkvndvvceqiangenaitgvmiesninegn
    qgipaegkaglkygvsitdacigwettedvlrklaaavrqrrevnk