PDB entry 1nzi

View 1nzi on RCSB PDB site
Description: Crystal Structure of the CUB1-EGF Interaction Domain of Complement Protease C1s
Class: hydrolase
Keywords: calcium, complement, innate immunity, modular structure, cub, egf
Deposited on 2003-02-18, released 2003-06-10
The last revision prior to the SCOP 1.73 freeze date was dated 2003-09-09, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.216
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Complement C1s component
    Species: HOMO SAPIENS
    Gene: C1S
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1nzia1, d1nzia2
  • Chain 'B':
    Compound: Complement C1s component
    Species: HOMO SAPIENS
    Gene: C1S
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1nzib1, d1nzib2
  • Heterogens: CA, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nziA (A:)
eptmygeilspnypqaypsevekswdievpegygihlyfthldielsencaydsvqiisg
dteegrlcgqrssnnphspiveefqvpynklqvifksdfsneerftgfaayyvatdinec
tdfvdvpcshfcnnfiggyfcscppeyflhddmkncgvn

    Sequence, based on observed residues (ATOM records): (download) 
    >1nziA (A:)
eptmygeilspnypqaypsevekswdievpegygihlyfthldielsencaydsvqiise
egrlcgqrssnnphspiveefqvpynklqvifksdfsneerftgfaayyvatdinectdv
dvpcshfcnnfiggyfcscppeyflhddmkncgvn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1nziB (B:)
eptmygeilspnypqaypsevekswdievpegygihlyfthldielsencaydsvqiisg
dteegrlcgqrssnnphspiveefqvpynklqvifksdfsneerftgfaayyvatdinec
tdfvdvpcshfcnnfiggyfcscppeyflhddmkncgvn

    Sequence, based on observed residues (ATOM records): (download) 
    >1nziB (B:)
tmygeilspnypqaypsevekswdievpegygihlyfthldielsencaydsvqiisgdt
eegrlcgqrssnphspiveefqvpynklqvifksdfsneerftgfaayyvatdinectdf
vdvpcshfcnnfiggyfcscppeyflhddmkncgvn