PDB entry 1nx0

View 1nx0 on RCSB PDB site
Description: Structure of Calpain Domain 6 in Complex with Calpastatin DIC
Class: hydrolase/hydrolase inhibitor
Keywords: CALCIUM BINDING, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2003-02-07, released 2003-08-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-05-02, with a file datestamp of 2012-04-27.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.218
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Calcium-dependent protease, small subunit
  Species: Sus scrofa [TaxId:9823]
  Gene: CAPNS1 OR CAPN4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P04574
  Domains in SCOPe 2.06: d1nx0a_
• Chain 'B':
  Compound: Calcium-dependent protease, small subunit
  Species: Sus scrofa [TaxId:9823]
  Gene: CAPNS1 OR CAPN4
  Database cross-references and differences (RAF-indexed):
  • Uniprot P04574 (0-172)
  Domains in SCOPe 2.06: d1nx0b_
• Chain 'C':
  Compound: Calpastatin
  Species: Sus scrofa [TaxId:9823]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P49342
    • conflict (11)
• Chain 'D':
  Compound: Calpastatin
  Species: Sus scrofa [TaxId:9823]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P49342 (0-End)
• Chain 'E':
  Compound: Small molecule inhibitor
  Species: synthetic, synthetic
  Database cross-references and differences (RAF-indexed):
  • PDB 1NX0 (0-4)
• Heterogens: CA, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1nx0A (A:)
  eevrqfrrlfaqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmvavmdsdt
  tgklgfeefkylwnnikkwqaiykqfdvdrsgtigsselpgafeaagfhlnehlysmiir
  rysdeggnmdfdnfisclvrldamfrafksldkdgtgqiqvniqewlqltmys
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1nx0B (B:)
  eevrqfrrlfaqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmvavmdsdt
  tgklgfeefkylwnnikkwqaiykqfdvdrsgtigsselpgafeaagfhlnehlysmiir
  rysdeggnmdfdnfisclvrldamfrafksldkdgtgqiqvniqewlqltmys
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.