PDB entry 1nsg
View 1nsg on RCSB PDB site
Description: the structure of the immunophilin-immunosuppressant fkbp12-rapamycin complex interacting with human frap
Class: complex (isomerase/kinase)
Keywords: COMPLEX (ISOMERASE-KINASE), TRANSFERASE, FKBP12, FRAP, RAPAMYCIN, COMPLEX (ISOMERASE-KINASE) complex
Deposited on
1997-07-01, released
1998-03-18
The last revision prior to the SCOPe 2.04 freeze date was dated
2013-09-18, with a file datestamp of
2013-09-13.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.196
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: fk506-binding protein
Species: Homo sapiens [TaxId:9606]
Gene: HUMAN HIPPOCAMPAL CDNA LIBRARY
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1nsga_ - Chain 'B':
Compound: fkbp-rapamycin associated protein (frap)
Species: Homo sapiens [TaxId:9606]
Gene: HUMAN HIPPOCAMPAL CDNA LIBRARY
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1nsgb_ - Heterogens: RAD, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1nsgA (A:)
gvqvetispgdgrtfpkrgqtcvvhytgmledgkkfdssrdrnkpfkfmlgkqevirgwe
egvaqmsvgqrakltispdyaygatghpgiipphatlvfdvellkle
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1nsgB (B:)
vailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdl
meaqewcrkymksgnvkdltqawdlyyhvfrris