PDB entry 1ns3

View 1ns3 on RCSB PDB site
Description: structure of hcv protease (bk strain)
Class: complex (hydrolase/peptide)
Keywords: HYDROLASE, SERINE PROTEINASE, COMPLEX (HYDROLASE-PEPTIDE), COMPLEX (HYDROLASE-PEPTIDE) complex
Deposited on 1997-04-05, released 1998-04-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.204
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NS3 protease
    Species: HEPATITIS C VIRUS [TaxId:11105]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26663 (Start-179)
      • conflict (65)
      • conflict (85-86)
      • conflict (146)
    Domains in SCOPe 2.06: d1ns3.1
  • Chain 'B':
    Compound: NS3 protease
    Species: HEPATITIS C VIRUS [TaxId:11105]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26663 (Start-179)
      • conflict (65)
      • conflict (85-86)
      • conflict (146)
    Domains in SCOPe 2.06: d1ns3.2
  • Chain 'C':
    Compound: ns4a peptide
    Species: HEPATITIS C VIRUS [TaxId:11105]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1ns3.1
  • Chain 'D':
    Compound: ns4a peptide
    Species: HEPATITIS C VIRUS [TaxId:11105]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1ns3.2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ns3A (A:)
maitaysqqtrgllgciitsltgrdknqvegevqvvstatqsflatcvngvcwtvyhgag
sktlagpkgpitqmytnvdqdlvgwqappgarsltpctcgssdlylvtrhadvipvrrrg
dsrgsllsprpvsylkgssggpllcpsghavgifraavctrgvakavdfvpvesmettmr
mrkkkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ns3A (A:)
itaysqqtrgllgciitsltgrdknqvegevqvvstatqsflatcvngvcwtvyhgagsk
tlagpkgpitqmytnvdqdlvgwqappgarsltpctcgssdlylvtrhadvipvrrrgds
rgsllsprpvsylkgssggpllcpsghavgifraavctrgvakavdfvpvesmettmr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ns3B (B:)
maitaysqqtrgllgciitsltgrdknqvegevqvvstatqsflatcvngvcwtvyhgag
sktlagpkgpitqmytnvdqdlvgwqappgarsltpctcgssdlylvtrhadvipvrrrg
dsrgsllsprpvsylkgssggpllcpsghavgifraavctrgvakavdfvpvesmettmr
mrkkkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ns3B (B:)
itaysqqtrgllgciitsltgrdknqvegevqvvstatqsflatcvngvcwtvyhgagsk
tlagpkgpitqmytnvdqdlvgwqappgarsltpctcgssdlylvtrhadvipvrrrgds
rgsllsprpvsylkgssggpllcpsghavgifraavctrgvakavdfvpvesmettmr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ns3C (C:)
kgsvvivgriilsk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ns3C (C:)
kgsvvivgriils

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ns3D (D:)
kgsvvivgriilsk

    Sequence, based on observed residues (ATOM records): (download) 
    >1ns3D (D:)
kgsvvivgriils