PDB entry 1nhx

View 1nhx on RCSB PDB site
Description: pepck complex with a GTP-competitive inhibitor
Class: lyase
Keywords: gluconeogenesis, xanthine, inhibitor, lyase
Deposited on 2002-12-19, released 2003-09-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.175
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoenolpyruvate carboxykinase, cytosolic
    Species: Homo sapiens [TaxId:9606]
    Gene: PCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35558 (Start-624)
      • variant (269)
      • variant (588)
      • variant (599)
    Domains in SCOPe 2.08: d1nhxa1, d1nhxa2
  • Heterogens: MN, NA, PEP, FTB, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1nhxA (A:)
    gelmppqlqnglnlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrll
    gqmeeegilrrlkkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwm
    seedfekafnarfpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmg
    tpvlealgdgefvkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgygg
    nsllgkkcfalrmasrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammn
    pslpgwkvecvgddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntif
    tnvaetsdggvywegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiid
    aawespegvpiegiifggrrpagvplvyealswqhgvfvgaamrseataaaehkgkiimh
    dpfamrpffgynfgkylahwlsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvl
    ewmfnridgkastkltpigyipkedalnlkglghinmmelfsiskefwdkevediekylv
    dqvnadlpceiereilalkqrisqm
    

    Sequence, based on observed residues (ATOM records): (download)
    >1nhxA (A:)
    nlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrllgqmeeegilrrl
    kkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwmseedfekafnar
    fpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmgtpvlealgdgef
    vkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgyggnsllgkkcfalr
    masrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvg
    ddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvy
    wegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpie
    giifggrrpagvplvyealswqhgvfvgaamrseakiimhdpfamrpffgynfgkylahw
    lsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgkastkltpigy
    ipkedalnlkglghinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkq
    risqm