PDB entry 1nh0

View 1nh0 on RCSB PDB site
Description: 1.03 A structure of HIV-1 protease: inhibitor binding inside and outside the active site
Class: hydrolase/hydrolase inhibitor
Keywords: aspartyl protease, human immunodeficiency virus, inhibitor design, hydrolase-hydrolase inhibitor complex
Deposited on 2002-12-18, released 2004-04-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.03 Å
R-factor: 0.131
AEROSPACI score: 0.98 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protease retropepsin
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nh0a_
  • Chain 'B':
    Compound: protease retropepsin
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1nh0b_
  • Chain 'I':
    Compound: peptidomimetic inhibitor KI2-PHE-GLU-GLU-NH2
    Database cross-references and differences (RAF-indexed):
    • PDB 1NH0 (0-End)
  • Chain 'J':
    Compound: peptidomimetic inhibitor KI2-PHE-GLU-GLU-NH2
    Database cross-references and differences (RAF-indexed):
    • PDB 1NH0 (0-End)
  • Heterogens: SO4, BME, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1nh0A (A:)
    pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1nh0B (B:)
    pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.