PDB entry 1nc4

View 1nc4 on RCSB PDB site
Description: Crystal Structure of Monoclonal Antibody 2D12.5 Fab Complexed with Gd-DOTA
Class: Immune system
Keywords: antibody-dota complex, rare earth, dota, metal chelate, gadolinium, gamma turn, n-linked glycosylation
Deposited on 2002-12-04, released 2003-12-16
The last revision prior to the SCOP 1.75 freeze date was dated 2003-12-16, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.208
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: monoclonal antibody 2d12.5, lambda light chain
    Species: Mus musculus
    Domains in SCOP 1.75: d1nc4a1, d1nc4a2
  • Chain 'B':
    Compound: monoclonal antibody 2d12.5, igg1 gamma heavy chain
    Species: Mus musculus
    Domains in SCOP 1.75: d1nc4b1, d1nc4b2
  • Chain 'C':
    Compound: monoclonal antibody 2d12.5, lambda light chain
    Species: Mus musculus
    Domains in SCOP 1.75: d1nc4c1, d1nc4c2
  • Chain 'D':
    Compound: monoclonal antibody 2d12.5, igg1 gamma heavy chain
    Species: Mus musculus
    Domains in SCOP 1.75: d1nc4d1, d1nc4d2
  • Heterogens: NAG, CL, DOF, GD3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nc4A (A:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlftgliggnnnrppgv
parfsgsligdkaaltiagtqtedeaiyfcalwysnhwvfgggtrltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslspaecs

    Sequence, based on observed residues (ATOM records): (download) 
    >1nc4A (A:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlftgliggnnnrppgv
parfsgsligdkaaltiagtqtedeaiyfcalwysnhwvfgggtrltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1nc4B (B:)
evklqesgpglvqpsqslsitctvsgfsltdygvhwvrqspgkglewlgviwsgggtayt
aafisrlniykdnsknqvffemnslqandtamyycarrgsypynyfdvwgqgttvtvssa
kttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdl
ytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

    Sequence, based on observed residues (ATOM records): (download) 
    >1nc4B (B:)
evklqesgpglvqpsqslsitctvsgfsltdygvhwvrqspgkglewlgviwsgggtayt
aafisrlniykdnsknqvffemnslqandtamyycarrgsypynyfdvwgqgttvtvssa
kttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdl
ytlsssvtvpsstwpsetvtcnvahpasstkvdkkivpr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1nc4C (C:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlftgliggnnnrppgv
parfsgsligdkaaltiagtqtedeaiyfcalwysnhwvfgggtrltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslspaecs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1nc4D (D:)
qvklqesgpglvqpsqslsitctvsgfsltdygvhwvrqspgkglewlgviwsgggtayt
aafisrlniykdnsknqvffemnslqandtamyycarrgsypynyfdvwgqgttvtvssa
kttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdl
ytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

    Sequence, based on observed residues (ATOM records): (download) 
    >1nc4D (D:)
qvklqesgpglvqpsqslsitctvsgfsltdygvhwvrqspgkglewlgviwsgggtayt
aafisrlniykdnsknqvffemnslqandtamyycarrgsypynyfdvwgqgttvtvssa
kttppsvyplapgssmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlss
svtvpsstwpsetvtcnvahpasstkvdkkivprd