PDB entry 1nc2

View 1nc2 on RCSB PDB site
Description: Crystal Structure of Monoclonal Antibody 2D12.5 Fab Complexed with Y-DOTA
Class: Immune system
Keywords: antibody-dota complex, rare earth, dota, metal chelate, yttrium, gamma turn, n-linked glycosylation
Deposited on 2002-12-04, released 2003-12-16
The last revision prior to the SCOP 1.73 freeze date was dated 2003-12-16, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.209
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: monoclonal antibody 2d12.5, lambda light chain
    Species: Mus musculus
    Domains in SCOP 1.73: d1nc2a1, d1nc2a2
  • Chain 'B':
    Compound: monoclonal antibody 2d12.5, igg1 gamma heavy chain
    Species: Mus musculus
    Domains in SCOP 1.73: d1nc2b1, d1nc2b2
  • Chain 'C':
    Compound: monoclonal antibody 2d12.5, lambda light chain
    Species: Mus musculus
    Domains in SCOP 1.73: d1nc2c1, d1nc2c2
  • Chain 'D':
    Compound: monoclonal antibody 2d12.5, igg1 gamma heavy chain
    Species: Mus musculus
    Domains in SCOP 1.73: d1nc2d1, d1nc2d2
  • Heterogens: NAG, YT3, CL, DOE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nc2A (A:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlftgliggnnnrppgv
parfsgsligdkaaltiagtqtedeaiyfcalwysnhwvfgggtrltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslspaecs

    Sequence, based on observed residues (ATOM records): (download) 
    >1nc2A (A:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlftgliggnnnrppgv
parfsgsligdkaaltiagtqtedeaiyfcalwysnhwvfgggtrltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1nc2B (B:)
evklqesgpglvqpsqslsitctvsgfsltdygvhwvrqspgkglewlgviwsgggtayt
aafisrlniykdnsknqvffemnslqandtamyycarrgsypynyfdvwgqgttvtvssa
kttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdl
ytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

    Sequence, based on observed residues (ATOM records): (download) 
    >1nc2B (B:)
evklqesgpglvqpsqslsitctvsgfsltdygvhwvrqspgkglewlgviwsgggtayt
aafisrlniykdnsknqvffemnslqandtamyycarrgsypynyfdvwgqgttvtvssa
kttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdl
ytlsssvtvpsstwpsetvtcnvahpasstkvdkkivpr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1nc2C (C:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlftgliggnnnrppgv
parfsgsligdkaaltiagtqtedeaiyfcalwysnhwvfgggtrltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslspaecs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1nc2D (D:)
qvklqesgpglvqpsqslsitctvsgfsltdygvhwvrqspgkglewlgviwsgggtayt
aafisrlniykdnsknqvffemnslqandtamyycarrgsypynyfdvwgqgttvtvssa
kttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdl
ytlsssvtvpsstwpsetvtcnvahpasstkvdkkivprdc

    Sequence, based on observed residues (ATOM records): (download) 
    >1nc2D (D:)
qvklqesgpglvqpsqslsitctvsgfsltdygvhwvrqspgkglewlgviwsgggtayt
aafisrlniykdnsknqvffemnslqandtamyycarrgsypynyfdvwgqgttvtvssa
kttppsvyplapgsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsss
vtvpsstwpsetvtcnvahpasstkvdkkivprdc