PDB entry 1mrv

View 1mrv on RCSB PDB site
Description: crystal structure of an inactive Akt2 kinase domain
Class: transferase
Keywords: AGC serine threonine kinase, AKT PKB kinase domain, tumorigenesis, x-ray crystal structure, signal transduction, TRANSFERASE
Deposited on 2002-09-18, released 2003-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.247
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RAC-beta serine/threonine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: AKT2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1mrva_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1mrvA (A:)
arakvtmndfdylkllgkgtfgkvilvrekatgryyamkilrkeviiakdevahtvtesr
vlqntrhpfltalkyafqthdrlcfvmeyanggelffhlsrervfteerarfygaeivsa
leylhsrdvvyrdiklenlmldkdghikitdfglckegisdgatmktfcgtpeylapevl
edndygravdwwglgvvmyemmcgrlpfynqdherlfelilmeeirfprtlspeakslla
gllkkdpkqrlgggpsdakevmehrfflsinwqdvvqkkllppfkpqvtsevdtryfdde
ftaqsititppdrydslglleldqrthfpqfsysasire

    Sequence, based on observed residues (ATOM records): (download) 
    >1mrvA (A:)
vtmndfdylkllgkgtfgkvilvrekatgryyamkilrkevivlqntrhpfltalkyafq
thdrlcfvmeyanggelffhlsrervfteerarfygaeivsaleylhsrdvvyrdiklen
lmldkdghikitdfpeylapevledndygravdwwglgvvmyemmcgrlpfynqdherlf
elilmeeirfprtlspeaksllagllkkdpkqrlgggpsdakevmehrfflsinwqdvvq
kkllppfkpqvtsevdtryfd