PDB entry 1mkk

View 1mkk on RCSB PDB site
Description: Disulfide deficient mutant of vascular endothelial growth factor A (C61A and C104A)
Class: hormone/growth factor
Keywords: Cystine-knot growth factor, HORMONE/GROWTH FACTOR COMPLEX
Deposited on 2002-08-29, released 2002-12-11
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.32 Å
R-factor: 0.168
AEROSPACI score: -1.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Vascular Endothelial Growth Factor A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15692 (1-End)
      • engineered (48)
      • engineered (91)
    Domains in SCOPe 2.01: d1mkka_
  • Chain 'B':
    Compound: Vascular Endothelial Growth Factor A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15692 (1-End)
      • cloning artifact (0)
      • engineered (48)
      • engineered (91)
    Domains in SCOPe 2.01: d1mkkb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1mkkA (A:)
mvvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggcandeglecvpte
esnitmqimrikphqgqhigemsflqhnkcearpkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1mkkA (A:)
vvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggcandeglecvptee
snitmqimrikphqgqhigemsflqhnkcearp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1mkkB (B:)
mvvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggcandeglecvpte
esnitmqimrikphqgqhigemsflqhnkcearpkk

    Sequence, based on observed residues (ATOM records): (download) 
    >1mkkB (B:)
mvvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggcandeglecvpte
esnitmqimrikphqgqhigemsflqhnkcearp