PDB entry 1mdm
View 1mdm on RCSB PDB site
Description: inhibited fragment of ets-1 and paired domain of pax5 bound to DNA
Class: transcription/DNA
Keywords: Transcription factor, ternary complex, X-ray diffraction, autoinhibition, ETS domain, Paired domain, TRANSCRIPTION/DNA COMPLEX
Deposited on
2002-08-07, released
2002-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.259
AEROSPACI score: 0.2
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: paired box protein pax-5
Species: Homo sapiens [TaxId:9606]
Gene: PAX5
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1mdma1, d1mdma2 - Chain 'B':
Compound: c-ets-1 protein
Species: Mus musculus [TaxId:10090]
Gene: ETS-1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1mdmb_ - Chain 'C':
Compound: Pax5/Ets Binding Site on the mb-1 promoter
Species: synthetic, synthetic
- Chain 'D':
Compound: Pax5/Ets Binding Site on the mb-1 promoter
Species: synthetic, synthetic
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1mdmA (A:)
mdleknyptprtsrtghggvnqlggvfvngrplpdvvrqrivelahqgvrpcdisrqlrv
shgcvskilgryyetgsikpgviggskpkvatpkvvekiaeykrqnptmfaweirdrlla
ervcdndtvpsvssinriirtkvqqppnq
Sequence, based on observed residues (ATOM records): (download)
>1mdmA (A:)
gvnqlggvfvngrplpdvvrqrivelahqgvrpcdisrqlrvshgcvskilgryyetgsi
kpgviggskpkvatpkvvekiaeykrqnptmfaweirdrllaervcdndtvpsvssinri
irtk
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1mdmB (B:)
vpsydsfdyedypaalpnhkpkgtfkdyvrdradlnkdkpvipaaalagytgsgpiqlwq
fllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyeklsrglryyydk
niihktagkryvyrfvcdlqsllgytpeelhamldvkpdad
Sequence, based on observed residues (ATOM records): (download)
>1mdmB (B:)
rdradlnkdkpvipaaalagytgsgpiqlwqfllelltdkscqsfiswtgdgwefklsdp
devarrwgkrknkpkmnyeklsrglryyydkniihktagkryvyrfvcdlqsllgytpee
lhamldvkp
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.