PDB entry 1m54

View 1m54 on RCSB PDB site
Description: cystathionine-beta synthase: reduced vicinal thiols
Class: lyase
Keywords: plp protein fold type II (tryptophan synthase), plp and heme bound to protein, reduced vicinal cysteines
Deposited on 2002-07-08, released 2002-08-14
The last revision prior to the SCOP 1.73 freeze date was dated 2002-08-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.271
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Gene: CBS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1m54a_
  • Chain 'B':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Gene: CBS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1m54b_
  • Chain 'C':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Gene: CBS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1m54c_
  • Chain 'D':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Gene: CBS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1m54d_
  • Chain 'E':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Gene: CBS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1m54e_
  • Chain 'F':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Gene: CBS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1m54f_
  • Heterogens: PLP, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1m54A (A:)
mrpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkc
ellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgy
rciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnshildqy
rnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpe
gsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqeg
llcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflkeedlt
ekk

    Sequence, based on observed residues (ATOM records): (download) 
    >1m54A (A:)
dapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkcell
akceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgyrci
ivmpekmssekvdvlralgaeivrtptnpeshvgvawrlkneipnshildqyrnasnpla
hydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilaepe
elnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggsag
stvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflkeedlt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1m54B (B:)
mrpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkc
ellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgy
rciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnshildqy
rnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpe
gsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqeg
llcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflkeedlt
ekk

    Sequence, based on observed residues (ATOM records): (download) 
    >1m54B (B:)
rpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkce
llakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgyr
ciivmpekmssekvdvlralgaeivrtptshvgvawrlkneipnshildqyrnasnplah
ydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilaepee
lnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggsags
tvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfeed

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1m54C (C:)
mrpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkc
ellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgy
rciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnshildqy
rnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpe
gsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqeg
llcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflkeedlt
ekk

    Sequence, based on observed residues (ATOM records): (download) 
    >1m54C (C:)
dapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkcell
akceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgyrci
ivmpekmssekvdvlralgaeivrtpteshvgvawrlkneipnshildqyrnasnplahy
dttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilaepeel
nqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggsagst
vavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflke

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1m54D (D:)
mrpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkc
ellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgy
rciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnshildqy
rnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpe
gsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqeg
llcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflkeedlt
ekk

    Sequence, based on observed residues (ATOM records): (download) 
    >1m54D (D:)
dapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkcell
akceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgyrci
ivmpekmssekvdvlralgaeivrtpteshvgvawrlkneipnshildqyrnasnplahy
dttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilaepeel
nqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggsagst
vavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflke

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1m54E (E:)
mrpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkc
ellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgy
rciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnshildqy
rnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpe
gsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqeg
llcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflkeedlt
ekk

    Sequence, based on observed residues (ATOM records): (download) 
    >1m54E (E:)
dapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkcell
akceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgyrci
ivmpekmssekvdvlralgaeivrtptdspeshvgvawrlkneipnshildqyrnasnpl
ahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilaep
eelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggsa
gstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1m54F (F:)
mrpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkc
ellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgy
rciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnshildqy
rnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpe
gsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqeg
llcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflkeedlt
ekk

    Sequence, based on observed residues (ATOM records): (download) 
    >1m54F (F:)
rpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglkce
llakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrgyr
ciivmpekmssekvdvlralgaeivrteshvgvawrlkneipnshildqyrnasnplahy
dttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilaepeel
nqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggsagst
vavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfl