PDB entry 1lwk

View 1lwk on RCSB PDB site
Description: Multiple Methionine Substitutions are Tolerated in T4 Lysozyme and have Coupled Effects on Folding and Stability
Class: hydrolase
Keywords: hydrolase (o-glycosyl), T4 lysozyme, methionine core mutant, protein engineering, protein folding
Deposited on 2002-05-31, released 2003-05-20
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.219
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: lysozyme
  Species: Enterobacteria phage T4 [TaxId:10665]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P00720 (0-End)
    • modified residue (0)
    • modified residue (5)
    • engineered (53)
    • engineered, modified residue (83)
    • engineered, modified residue (86)
    • engineered, modified residue (90)
    • engineered (96)
    • engineered, modified residue (98)
    • modified residue (101)
    • modified residue (105)
    • engineered (109)
    • engineered, modified residue (110)
    • engineered, modified residue (117)
    • modified residue (119)
    • engineered, modified residue (120)
    • engineered, modified residue (132)
    • engineered, modified residue (152)
  Domains in SCOPe 2.01: d1lwka_
• Heterogens: CL, HED, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >1lwkA (A:)
  mnifemlrideglrlkiykdtegyytigighlltkspslnaakseldkaigrntngvitk
  deaeklfnqdvdaavrgilrnakmkpmydsmdavrraaminmvfqmgetrmagftnsmrm
  mqqkrwdeaavnmaksrwynqtpnrakrvittmrtgtwdayknl
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >1lwkA (A:)
  mnifemlrideglrlkiykdtegyytigighlltkspslnaakseldkaigrntngvitk
  deaeklfnqdvdaavrgilrnakmkpmydsmdavrraaminmvfqmgetrmagftnsmrm
  mqqkrwdeaavnmaksrwynqtpnrakrvittmrtgtwdayk