PDB entry 1lo5

View 1lo5 on RCSB PDB site
Description: Crystal structure of the D227A variant of Staphylococcal enterotoxin A in complex with human MHC class II
Class: IMMUNE SYSTEM/Toxin
Keywords: protein-protein complex
Deposited on 2002-05-06, released 2002-12-18
The last revision prior to the SCOP 1.75 freeze date was dated 2003-09-30, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.245
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1lo5a1, d1lo5a2
  • Chain 'B':
    Compound: hla class II histocompatibility antigen, dr-1 beta chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1lo5b1, d1lo5b2
  • Chain 'C':
    Compound: Hemagglutinin peptide
    Species: synthetic, synthetic
  • Chain 'D':
    Compound: enterotoxin A
    Species: Staphylococcus aureus
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0L2 (0-232)
      • engineered (226)
    Domains in SCOP 1.75: d1lo5d1, d1lo5d2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1lo5A (A:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    da
    

    Sequence, based on observed residues (ATOM records): (download)
    >1lo5A (A:)
    ehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalani
    avdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwlr
    ngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefda
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1lo5B (B:)
    gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
    wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvs
    gfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1lo5B (B:)
    trprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaeywn
    sqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvsgf
    ypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsvts
    pltvewra
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1lo5D (D:)
    sekseeinekdlrkkselqgtalgnlkqiyyynekaktenkeshdqflqhtilfkgfftd
    hswyndllvdfdskdivdkykgkkvdlygayygyqcaggtpnktacmyggvtlhdnnrlt
    eekkvpinlwldgkqntvpletvktnkknvtvqeldlqarrylqekynlynsdvfdgkvq
    rglivfhtstepsvnydlfgaqgqysntllriyrdnktinsenmhiaiylyts