PDB entry 1l8a

View 1l8a on RCSB PDB site
Description: e. coli pyruvate dehydrogenase
Class: oxidoreductase
Keywords: thiamin diphosphate, pyruvate, alpha-keto acid dehydrogenase
Deposited on 2002-03-19, released 2002-07-24
The last revision prior to the SCOP 1.75 freeze date was dated 2002-07-24, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.189
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyruvate dehydrogenase E1 component
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1l8aa1, d1l8aa2, d1l8aa3
  • Chain 'B':
    Compound: Pyruvate dehydrogenase E1 component
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1l8ab1, d1l8ab2, d1l8ab3
  • Heterogens: MG, TDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1l8aA (A:)
serfpndvdpietrdwlqaiesvireegveraqylidqllaearkggvnvaagtgisnyi
ntipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssatiydvc
fnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgnglssyphp
klmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemdepeskg
aitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwgsrwde
llrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeqiwaln
rgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaaegkniahqvkkmnmdgvrhi
rdrfnvpvsdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqd
fgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiysp
ngqqytpqdreqvayykedekgqilqeginelgagcswlaaatsystnnlpmipfyiyys
mfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipncisydp
ayayevavimhdglermygekqenvyyyittlnenyhmpampegaeegirkgiykletie
gskgkvqllgsgsilrhvreaaeilakdygvgsdvysvtsftelardgqdcerwnmlhpl
etprvpyiaqvmndapavastdymklfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhh
fevdasyvvvaalgelakrgeidkkvvadaiakfnidadkvnprla

    Sequence, based on observed residues (ATOM records): (download) 
    >1l8aA (A:)
isnyintipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssat
iydvcfnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgngls
syphpklmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemde
peskgaitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwg
srwdellrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeq
iwalnrgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaamdgvrhirdrfnvpv
sdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqdfgalleeq
skeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiyspedekgqil
qeginelgagcswlaaatsystnnlpmipfyiyysmfgfqrigdlcwaagdqqargflig
gtsgrttlngeglqhedghshiqsltipncisydpayayevavimhdglermygekqenv
yyyittlnenyhmpampegaeegirkgiykletiegskgkvqllgsgsilrhvreaaeil
akdygvgsdvysvtsftelardgqdcerwnmlhpletprvpyiaqvmndapavastdymk
lfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhhfevdasyvvvaalgelakrgeidkk
vvadaiakfnidadkvnprla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1l8aB (B:)
serfpndvdpietrdwlqaiesvireegveraqylidqllaearkggvnvaagtgisnyi
ntipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssatiydvc
fnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgnglssyphp
klmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemdepeskg
aitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwgsrwde
llrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeqiwaln
rgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaaegkniahqvkkmnmdgvrhi
rdrfnvpvsdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqd
fgalleeqskeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiysp
ngqqytpqdreqvayykedekgqilqeginelgagcswlaaatsystnnlpmipfyiyys
mfgfqrigdlcwaagdqqargfliggtsgrttlngeglqhedghshiqsltipncisydp
ayayevavimhdglermygekqenvyyyittlnenyhmpampegaeegirkgiykletie
gskgkvqllgsgsilrhvreaaeilakdygvgsdvysvtsftelardgqdcerwnmlhpl
etprvpyiaqvmndapavastdymklfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhh
fevdasyvvvaalgelakrgeidkkvvadaiakfnidadkvnprla

    Sequence, based on observed residues (ATOM records): (download) 
    >1l8aB (B:)
isnyintipveeqpeypgnlelerrirsairwnaimtvlraskkdlelgghmasfqssat
iydvcfnhffrarneqdggdlvyfqghispgvyaraflegrltqeqldnfrqevhgngls
syphpklmpefwqfptvsmglgpigaiyqakflkylehrglkdtskqtvyaflgdgemde
peskgaitiatrekldnlvfvincnlqrldgpvtgngkiinelegifegagwnvikvmwg
srwdellrkdtsgkliqlmnetvdgdyqtfkskdgayvrehffgkypetaalvadwtdeq
iwalnrgghdpkkiyaafkkaqetkgkatvilahtikgygmgdaamdgvrhirdrfnvpv
sdadieklpyitfpegseehtylhaqrqklhgylpsrqpnfteklelpslqdfgalleeq
skeisttiafvralnvmlknksikdrlvpiiadeartfgmeglfrqigiyspedekgqil
qeginelgagcswlaaatsystnnlpmipfyiyysmfgfqrigdlcwaagdqqargflig
gtsgrttlngeglqhedghshiqsltipncisydpayayevavimhdglermygekqenv
yyyittlnenyhmpampegaeegirkgiykletiegskgkvqllgsgsilrhvreaaeil
akdygvgsdvysvtsftelardgqdcerwnmlhpletprvpyiaqvmndapavastdymk
lfaeqvrtyvpaddyrvlgtdgfgrsdsrenlrhhfevdasyvvvaalgelakrgeidkk
vvadaiakfnidadkvnprla