PDB entry 1l5g

View 1l5g on RCSB PDB site
Description: crystal structure of the extracellular segment of integrin avb3 in complex with an arg-gly-asp ligand
Class: cell adhesion
Keywords: genu, hybrid domain, beta-tail domain, psi domain, egf domain, midas, admidas, limbs, cage motif, propeller, a-domain, thigh domain, calf domain, rgd ligand, cell adhesion
Deposited on 2002-03-06, released 2002-04-17
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.248
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrin alpha v
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • GB XP_002379 (0-End)
    Domains in SCOPe 2.03: d1l5ga1, d1l5ga2, d1l5ga3, d1l5ga4
  • Chain 'B':
    Compound: integrin beta-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1l5gb1, d1l5gb2, d1l5gb3, d1l5gb4, d1l5gb5
  • Chain 'C':
    Compound: cyclic arg-gly-asp peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1L5G (0-4)
  • Heterogens: NAG, MN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1l5gA (A:)
fnldvdspaeysgpegsyfgfavdffvpsassrmfllvgapkanttqpgiveggqvlkcd
wsstrrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkq
erepvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywq
gqlisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfv
sgvpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplf
mdrgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiai
aapyggedkkgivyifngrstglnavpsqilegqwaarsmppsfgysmkgatdidkngyp
dlivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclk
adgkgvlprklnfqvellldklkqkgairralflysrspshsknmtisrgglmqceelia
ylrdesefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahilldcgedn
vckpklevsvdsdqkkiyigddnpltlivkaqnqgegayeaelivsiplqadfigvvrnn
ealarlscafktenqtrqvvcdlgnpmkagtqllaglrfsvhqqsemdtsvkfdlqiqss
nlfdkvspvvshkvdlavlaaveirgvsspdhvflpipnwehkenpeteedvgpvvqhiy
elrnngpssfskamlhlqwpykynnntllyilhydidgpmnctsdmeinplrikisslqt
tekndtvagqgerdhlitkrdlalsegdihtlgcgvaqclkivcqvgrldrgksailyvk
sllwtetfmnkenqnhsyslkssasfnviefpyknlpieditnstlvttnvtwgiqp

    Sequence, based on observed residues (ATOM records): (download) 
    >1l5gA (A:)
fnldvdspaeysgpegsyfgfavdffvpsassrmfllvgapkanttqpgiveggqvlkcd
wsstrrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkq
erepvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywq
gqlisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfv
sgvpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplf
mdrgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiai
aapyggedkkgivyifngrstglnavpsqilegqwaarsmppsfgysmkgatdidkngyp
dlivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclk
adgkgvlprklnfqvellldklkqkgairralflysrspshsknmtisrgglmqceelia
ylrdesefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahilldcgedn
vckpklevsvdsdqkkiyigddnpltlivkaqnqgegayeaelivsiplqadfigvvrnn
ealarlscafktenqtrqvvcdlgnpmkagtqllaglrfsvhqqsemdtsvkfdlqiqss
nlfdkvspvvshkvdlavlaaveirgvsspdhvflpipnwehkenpeteedvgpvvqhiy
elrnngpssfskamlhlqwpykynnntllyilhydidgpmnctsdmeinplrikissldi
htlgcgvaqclkivcqvgrldrgksailyvksllwtetfmnkenqnhsyslkssasfnvi
efpyknlpieditnstlvttnvtwgiq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1l5gB (B:)
gpnicttrgvsscqqclavspmcawcsdealplgsprcdlkenllkdncapesiefpvse
arvledrplsdkgsgdssqvtqvspqrialrlrpddsknfsiqvrqvedypvdiyylmdl
sysmkddlwsiqnlgtklatqmrkltsnlrigfgafvdkpvspymyisppealenpcydm
kttclpmfgykhvltltdqvtrfneevkkqsvsrnrdapeggfdaimqatvcdekigwrn
dashllvfttdakthialdgrlagivqpndgqchvgsdnhysasttmdypslglmtekls
qkninlifavtenvvnlyqnyselipgttvgvlsmdssnvlqlivdaygkirskvelevr
dlpeelslsfnatclnnevipglkscmglkigdtvsfsieakvrgcpqekeksftikpvg
fkdslivqvtfdcdcacqaqaepnshrcnngngtfecgvcrcgpgwlgsqcecseedyrp
sqqdecspregqpvcsqrgeclcgqcvchssdfgkitgkycecddfscvrykgemcsghg
qcscgdclcdsdwtgyycncttrtdtcmssngllcsgrgkcecgscvciqpgsygdtcek
cptcpdactfkkecveckkfdrepymtentcnrycrdeiesvkelkdtgkdavnctykne
ddcvvrfqyyedssgksilyvveepecpkgpd

    Sequence, based on observed residues (ATOM records): (download) 
    >1l5gB (B:)
efpvsearvledrplsdkgsgdssqvtqvspqrialrlrpddsknfsiqvrqvedypvdi
yylmdlsysmkddlwsiqnlgtklatqmrkltsnlrigfgafvdkpvspymyisppeale
npcydmkttclpmfgykhvltltdqvtrfneevkkqsvsrnrdapeggfdaimqatvcde
kigwrndashllvfttdakthialdgrlagivqpndgqchvgsdnhysasttmdypslgl
mteklsqkninlifavtenvvnlyqnyselipgttvgvlsmdssnvlqlivdaygkirsk
velevrdlpeelslsfnatclnnevipglkscmglkigdtvsfsieakvrgcpqekeksf
tikpvgfkdslivqvtfdcdkgemcsghgqcscgdclcdsdwtgyycncttrtdtcmssn
gllcsgrgkcecgscvciqpgsygdtcekcptcpdactfkkecveckkfdrepymtentc
nrycrdeiesvkelkdtgkdavnctykneddcvvrfqyyedssgksilyvveepecpkg

  • Chain 'C':
    No sequence available.