PDB entry 1kps

View 1kps on RCSB PDB site
Description: Structural Basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin conjugating enzyme Ubc9 and RanGAP1
Class: ligase/protein transport
Keywords: sumo, ubiquitin, e2, conjugating enzyme, ligase, thioester, small ubiquitin-like modifier, ligase/protein transport complex
Deposited on 2002-01-02, released 2002-02-13
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.223
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin-like protein SUMO-1 conjugating enzyme
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC9
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63279 (1-158)
      • cloning artifact (0)
    Domains in SCOPe 2.02: d1kpsa_
  • Chain 'B':
    Compound: Ran-GTPase activating protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: RANGAP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1kpsb_
  • Chain 'C':
    Compound: Ubiquitin-like protein SUMO-1 conjugating enzyme
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1kpsc_
  • Chain 'D':
    Compound: Ran-GTPase activating protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: RANGAP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1kpsd_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kpsA (A:)
smsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfk
lrmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqel
lnepniqdpaqaeaytiycqnrveyekrvraqakkfaps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1kpsB (B:)
snsgepapvlssptptdlstflsfpspekllrlgpkvsvlivqqtdtsdpekvvsaflkv
asvfrddasvktavldaidalmkkafscssfnsntfltrllihmgllksedkikaipslh
gplmvlnhvvrqdyfpkalaplllafvtkpngaletcsfarhnllqtlyni

    Sequence, based on observed residues (ATOM records): (download) 
    >1kpsB (B:)
tdlstflsfpspekllrlgpkvsvlivqqtdtsdpekvvsaflkvasvfrddasvktavl
daidalmkkafscssfnsntfltrllihmgllksedkikaipslhgplmvlnhvvrqdyf
pkalaplllafvtkpngaletcsfarhnllqtlyni

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1kpsC (C:)
smsgialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfk
lrmlfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqel
lnepniqdpaqaeaytiycqnrveyekrvraqakkfaps

    Sequence, based on observed residues (ATOM records): (download) 
    >1kpsC (C:)
gialsrlaqerkawrkdhpfgfvavptknpdgtmnlmnwecaipgkkgtpwegglfklrm
lfkddypssppkckfepplfhpnvypsgtvclsileedkdwrpaitikqillgiqellne
pniqdpaqaeaytiycqnrveyekrvraqakkfaps

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1kpsD (D:)
snsgepapvlssptptdlstflsfpspekllrlgpkvsvlivqqtdtsdpekvvsaflkv
asvfrddasvktavldaidalmkkafscssfnsntfltrllihmgllksedkikaipslh
gplmvlnhvvrqdyfpkalaplllafvtkpngaletcsfarhnllqtlyni

    Sequence, based on observed residues (ATOM records): (download) 
    >1kpsD (D:)
dlstflsfpspekllrlgpkvsvlivqqtdtsdpekvvsaflkvasvfrddasvktavld
aidalmkkafscssfnsntfltrllihmgllksedkikaipslhgplmvlnhvvrqdyfp
kalaplllafvtkpngaletcsfarhnllqtlyni