PDB entry 1koo

View 1koo on RCSB PDB site
Description: the crystal structure and mutational analysis of a novel RNA-binding domain found in the human tap nuclear mRNA export factor
Class: RNA binding protein
Keywords: mRNA export factor, Constitutive transport element (CTE), Ribonucleoprotein (RNP) and Leucine Rich Repeat (LRR) domains, RNA BINDING PROTEIN
Deposited on 2001-12-21, released 2002-02-27
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.8 Å
R-factor: 0.317
AEROSPACI score: -0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (156)
    Domains in SCOPe 2.03: d1kooa1, d1kooa2
  • Chain 'B':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (156)
    Domains in SCOPe 2.03: d1koob_
  • Chain 'C':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (156)
    Domains in SCOPe 2.03: d1kooc1, d1kooc2
  • Chain 'D':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9 (Start-276)
      • engineered (156)
    Domains in SCOPe 2.03: d1kood_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1kooA (A:)
vrrdrapperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhye
ntraqffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlkli
mskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnn
rlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqs
tyisairerfpkllrldghelpppiafdveapttlpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kooA (A:)
rggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhyentraqffve
dastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskrydgsq
qaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnnrlyrlddms
sivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqstyisairer
fpkllrldghelpppiaf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1kooB (B:)
vrrdrapperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhye
ntraqffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlkli
mskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnn
rlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqs
tyisairerfpkllrldghelpppiafdveapttlpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kooB (B:)
elkpeqveqlklimskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriiee
nipellslnlsnnrlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwl
dgnslcdtfrdqstyisairerfpkllrldghelpppiafdveap

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1kooC (C:)
vrrdrapperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhye
ntraqffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlkli
mskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnn
rlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqs
tyisairerfpkllrldghelpppiafdveapttlpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kooC (C:)
apperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhyentraq
ffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskry
dgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnnrlyrl
ddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqstyisa
irerfpkllrldghelpppiaf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1kooD (D:)
vrrdrapperggagtsqdgtsknwfkitipygrkydkawllsmiqskcsvpftpiefhye
ntraqffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlkli
mskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnn
rlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslcdtfrdqs
tyisairerfpkllrldghelpppiafdveapttlpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kooD (D:)
lkpeqveqlklimskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieen
ipellslnlsnnrlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwld
gnslcdtfrdqstyisairerfpkllrldghelpppiafdveapttlpp