PDB entry 1koh

View 1koh on RCSB PDB site
Description: the crystal structure and mutational analysis of a novel RNA-binding domain found in the human tap nuclear mRNA export factor
Class: RNA binding protein
Keywords: mRNA export factor, Constitutive transport element (CTE) Ribonucleoprotein (RNP) and Leucine Rich Repeat (LRR) domains, RNA BINDING PROTEIN
Deposited on 2001-12-20, released 2002-02-27
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.8 Å
R-factor: 0.275
AEROSPACI score: 0 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (47)
      • engineered (156)
      • engineered (232)
    Domains in SCOPe 2.06: d1koha1, d1koha2
  • Chain 'B':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (156)
      • engineered (232)
    Domains in SCOPe 2.06: d1kohb_
  • Chain 'C':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9
      • engineered (47)
      • engineered (156)
      • engineered (232)
    Domains in SCOPe 2.06: d1kohc1, d1kohc2
  • Chain 'D':
    Compound: tip associating protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UBU9 (Start-276)
      • engineered (156)
      • engineered (232)
    Domains in SCOPe 2.06: d1kohd_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1kohA (A:)
vrrdrapperggagtsqdgtsknwfkitipygrkydkawllsmiqskssvpftpiefhye
ntraqffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlkli
mskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnn
rlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslsdtfrdqs
tyisairerfpkllrldghelpppiafdveapttlpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kohA (A:)
rggagtsqdgtsknwfkitipygrkydkawllsmiqskssvpftpiefhyentraqffve
dastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskrydgsq
qaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnnrlyrlddms
sivqkapnlkilnlsgnelksereldkikglkleelwldgnslsdtfrdqstyisairer
fpkllrldghelpppiaf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1kohB (B:)
vrrdrapperggagtsqdgtsknwfkitipygrkydkawllsmiqskssvpftpiefhye
ntraqffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlkli
mskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnn
rlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslsdtfrdqs
tyisairerfpkllrldghelpppiafdveapttlpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kohB (B:)
lnelkpeqveqlklimskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlrii
eenipellslnlsnnrlyrlddmssivqkapnlkilnlsgnelksereldkikglkleel
wldgnslsdtfrdqstyisairerfpkllrldghelpppiafdveap

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1kohC (C:)
vrrdrapperggagtsqdgtsknwfkitipygrkydkawllsmiqskssvpftpiefhye
ntraqffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlkli
mskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnn
rlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslsdtfrdqs
tyisairerfpkllrldghelpppiafdveapttlpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kohC (C:)
erggagtsqdgtsknwfkitipygrkydkawllsmiqskssvpftpiefhyentraqffv
edastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlklimskrydgs
qqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnnrlyrlddm
ssivqkapnlkilnlsgnelksereldkikglkleelwldgnslsdtfrdqstyisaire
rfpkllrldghelpppiaf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1kohD (D:)
vrrdrapperggagtsqdgtsknwfkitipygrkydkawllsmiqskssvpftpiefhye
ntraqffvedastasalkavnykildrenrrisiiinssapphtilnelkpeqveqlkli
mskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlriieenipellslnlsnn
rlyrlddmssivqkapnlkilnlsgnelksereldkikglkleelwldgnslsdtfrdqs
tyisairerfpkllrldghelpppiafdveapttlpp

    Sequence, based on observed residues (ATOM records): (download) 
    >1kohD (D:)
lnelkpeqveqlklimskrydgsqqaldlkglrsdpdlvaqnidvvlnrrssmaatlrii
eenipellslnlsnnrlyrlddmssivqkapnlkilnlsgnelksereldkikglkleel
wldgnslsdtfrdqstyisairerfpkllrldghelpppiafdveapttlpp