PDB entry 1k93

View 1k93 on RCSB PDB site
Description: Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin
Class: toxin,lyase/metal binding protein
Keywords: edema factor, calmodulin, adenylyl cyclase, anthrax, TOXIN,LYASE/METAL BINDING PROTEIN COMPLEX
Deposited on 2001-10-26, released 2002-01-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.95 Å
R-factor: 0.278
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1k93a_
  • Chain 'B':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1k93b_
  • Chain 'C':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1k93c_
  • Chain 'D':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1k93d_
  • Chain 'E':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1k93e_
  • Chain 'F':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1k93f_
  • Heterogens: SO4, CA

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1k93A (A:)
    dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
    hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
    eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
    wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
    nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
    neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
    kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
    ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
    iefkllykqlnftenetdnfevfqkiidek
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k93A (A:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrsssvkkiagylsdyynsanhifsqekkrkisifrgiqay
    neienvlkskqiapeyknyfqylkeritnqvqlllthqkfkllykqlnftenetdnfevf
    qkiid
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1k93B (B:)
    dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
    hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
    eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
    wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
    nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
    neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
    kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
    ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
    iefkllykqlnftenetdnfevfqkiidek
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k93B (B:)
    dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
    ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
    kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
    ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtnll
    ikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdnei
    fiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkak
    intipsvkkiagylsdyynsanhifsqekkrkisifrgiqayneienvlkskqiapeykn
    yfqylkeritnqvqlllthqkfkllykqlnftenetdnfevfqkiid
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1k93C (C:)
    dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
    hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
    eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
    wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
    nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
    neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
    kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
    ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
    iefkllykqlnftenetdnfevfqkiidek
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k93C (C:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
    fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqkfkl
    lykqlnftenetdnfevfqkiid
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1k93D (D:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k93D (D:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1k93E (E:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k93E (E:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1k93F (F:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k93F (F:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta