PDB entry 1k90

View 1k90 on RCSB PDB site
Description: Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP
Class: toxin,lyase/metal binding protein
Keywords: oedema factor adenylyl cyclase anthrax calmodulin, TOXIN,LYASE-METAL BINDING PROTEIN COMPLEX
Deposited on 2001-10-26, released 2002-01-23
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.215
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1k90a_
  • Chain 'B':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1k90b_
  • Chain 'C':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1k90c_
  • Chain 'D':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1k90d_
  • Chain 'E':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1k90e_
  • Chain 'F':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1k90f_
  • Heterogens: CA, YB, 3AT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1k90A (A:)
    dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
    hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
    eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
    wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
    nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
    neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
    kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
    ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
    iefkllykqlnftenetdnfevfqkiidek
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k90A (A:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrsssvkkiagylsdyynsanhifsqekkrkisifrgiqay
    neienvlkskqiapeyknyfqylkeritnqvqlllthqkfkllykqlnftenetdnfevf
    qkiid
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1k90B (B:)
    dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
    hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
    eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
    wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
    nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
    neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
    kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
    ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
    iefkllykqlnftenetdnfevfqkiidek
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k90B (B:)
    dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
    ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
    kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
    ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnekqkgvtnllik
    ygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdneifi
    inpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkakin
    tipsvkkiagylsdyynsanhifsqekkrkisifrgiqayneienvlkskqiapeyknyf
    qylkeritnqvqlllthqkfkllykqlnftenetdnfevfqkiid
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1k90C (C:)
    dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
    hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
    eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
    wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
    nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
    neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
    kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
    ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
    iefkllykqlnftenetdnfevfqkiidek
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k90C (C:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
    fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqkfkl
    lykqlnftenetdnfevfqkiid
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1k90D (D:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k90D (D:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1k90E (E:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k90E (E:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1k90F (F:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k90F (F:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta