PDB entry 1k4w

View 1k4w on RCSB PDB site
Description: X-ray structure of the orphan nuclear receptor ROR beta ligand-binding domain in the active conformation
Class: hormone/growth factor
Keywords: ligand-binding domain, alpha-helical sandwich, transcriptionally active conformation, HORMONE-GROWTH FACTOR COMPLEX
Deposited on 2001-10-09, released 2002-04-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-21, with a file datestamp of 2021-07-16.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor ROR-beta
    Species: Rattus norvegicus [TaxId:10116]
    Gene: NR1F2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1k4wa_
  • Chain 'B':
    Compound: steroid receptor coactivator-1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • GB AAB50242 (0-14)
  • Heterogens: STE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1k4wA (A:)
    gqlapgitmseidriaqniikshletcqytmeelhqlawqthtyeeikayqsksrealwq
    qcaiqithaiqyvvefakritgfmelcqndqilllksgclevvlvrmcrafnplnntvlf
    egkyggmqmfkalgsddlvneafdfaknlcslqlteeeialfssavlispdrawlleprk
    vqklqekiyfalqhviqknhlddetlakliakiptitavcnlhgeklqvfkqshpdivnt
    lfpplykelfnp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1k4wA (A:)
    tmseidriaqniikshletcqytmeelhqlawqthtyeeikayqsksrealwqqcaiqit
    haiqyvvefakritgfmelcqndqilllksgclevvlvrmcrafnplnntvlfegkyggm
    qmfkalgsddlvneafdfaknlcslqlteeeialfssavlispdrawlleprkvqklqek
    iyfalqhviqknhlddetlakliakiptitavcnlhgeklqvfkqshpdivntlfpplyk
    elfn
    

  • Chain 'B':
    No sequence available.