PDB entry 1k2d
View 1k2d on RCSB PDB site
Description: Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at 2.2A
Class: immune system
Keywords: MHC class II, I-Au, H-2u, autoimmune disease, unique register, experimental autoimmune encephalomyelitis, myelin basic protein, IMMUNE SYSTEM
Deposited on
2001-09-26, released
2003-03-04
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-25.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.248
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: H-2 class II histocompatibility antigen, A-U alpha chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1k2da1, d1k2da2 - Chain 'B':
Compound: H-2 class II histocompatibility antigen, A-U beta chain
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d1k2db1, d1k2db2 - Chain 'P':
Compound: Myelin Basic Protein peptide with 8 residue linker peptide
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- GB XP_040888 (4-End)
- cloning artifact (1-3)
- conflict (4)
- Heterogens: NDG, NAG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1k2dA (A:)
hsrgeddieadhvgsygivvyqspgdigqytfefdgdelfyvdldkketiwmlpefaqlr
sfdpqgglqniatgkhnlgvltkrsnstpatneapqatvfpkspvllgqpntlicfvdni
fppvinitwlrnsksvadgvyetsffvnrdysfhklsyltfipsdddiydckvehwglee
pvlkhwepe
Sequence, based on observed residues (ATOM records): (download)
>1k2dA (A:)
ieadhvgsygivvyqspgdigqytfefdgdelfyvdldkketiwmlpefaqlrsfdpqgg
lqniatgkhnlgvltkrsnstpatneapqatvfpkspvllgqpntlicfvdnifppvini
twlrnsksvadgvyetsffvnrdysfhklsyltfipsdddiydckvehwgleepvlkhwe
pe
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1k2dB (B:)
gdserhfvvqfqpfcyftngtqriryvtryiynreeylrfdsdvgeyravtelgrpdaey
ynkqylertraeldtvcrynyeetevptslrrleqpnvvislsrtealnhhntlvcsvtd
fypakikvrwfrngqeetvgvsstqlirngdwtfqvlvmlemtprrgevytchvehpslk
spitvewra
Sequence, based on observed residues (ATOM records): (download)
>1k2dB (B:)
rhfvvqfqpfcyftngtqriryvtryiynreeylrfdsdvgeyravtelgrpdaeyynkq
ylertraeldtvcrynyeetevptslrrleqpnvvislsrtealnhhntlvcsvtdfypa
kikvrwfrngqeetvgvsstqlirngdwtfqvlvmlemtprrgevytchvehpslkspit
vewra
- Chain 'P':
No sequence available.