PDB entry 1jbq

View 1jbq on RCSB PDB site
Description: structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate dependent hemeprotein
Class: lyase
Keywords: Fold type II of PLP enzymes
Deposited on 2001-06-06, released 2001-08-12
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.257
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jbqa_
  • Chain 'B':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jbqb_
  • Chain 'C':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jbqc_
  • Chain 'D':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jbqd_
  • Chain 'E':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jbqe_
  • Chain 'F':
    Compound: cystathionine beta-synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jbqf_
  • Heterogens: HEM, PLP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1jbqA (A:)
gipsetpqaevgptsacgvslgipsetpqaevgptgcphrsgphsakgslekgspedkea
keplwirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkk
fglkcellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaa
avrgyrciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnsh
ildqyrnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcrii
gvdpegsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarml
iaqegllcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflk
eedltekkpwwwhlr

    Sequence, based on observed residues (ATOM records): (download) 
    >1jbqA (A:)
wirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglk
cellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrg
yrciivmpekmssekvdvlralgaeivrtpteshvgvawrlkneipnshildqyrnasnp
lahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilae
peelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggs
agstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1jbqB (B:)
gipsetpqaevgptsacgvslgipsetpqaevgptgcphrsgphsakgslekgspedkea
keplwirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkk
fglkcellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaa
avrgyrciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnsh
ildqyrnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcrii
gvdpegsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarml
iaqegllcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflk
eedltekkpwwwhlr

    Sequence, based on observed residues (ATOM records): (download) 
    >1jbqB (B:)
wirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglk
cellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrg
yrciivmpekmssekvdvlralgaeivrtpteshvgvawrlkneipnshildqyrnasnp
lahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilae
peelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggs
agstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1jbqC (C:)
gipsetpqaevgptsacgvslgipsetpqaevgptgcphrsgphsakgslekgspedkea
keplwirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkk
fglkcellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaa
avrgyrciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnsh
ildqyrnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcrii
gvdpegsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarml
iaqegllcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflk
eedltekkpwwwhlr

    Sequence, based on observed residues (ATOM records): (download) 
    >1jbqC (C:)
wirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglk
cellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrg
yrciivmpekmssekvdvlralgaeivrtpteshvgvawrlkneipnshildqyrnasnp
lahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilae
peelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggs
agstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1jbqD (D:)
gipsetpqaevgptsacgvslgipsetpqaevgptgcphrsgphsakgslekgspedkea
keplwirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkk
fglkcellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaa
avrgyrciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnsh
ildqyrnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcrii
gvdpegsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarml
iaqegllcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflk
eedltekkpwwwhlr

    Sequence, based on observed residues (ATOM records): (download) 
    >1jbqD (D:)
wirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglk
cellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrg
yrciivmpekmssekvdvlralgaeivrtpteshvgvawrlkneipnshildqyrnasnp
lahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilae
peelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggs
agstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfl

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1jbqE (E:)
gipsetpqaevgptsacgvslgipsetpqaevgptgcphrsgphsakgslekgspedkea
keplwirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkk
fglkcellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaa
avrgyrciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnsh
ildqyrnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcrii
gvdpegsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarml
iaqegllcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflk
eedltekkpwwwhlr

    Sequence, based on observed residues (ATOM records): (download) 
    >1jbqE (E:)
wirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglk
cellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrg
yrciivmpekmssekvdvlralgaeivrtpteshvgvawrlkneipnshildqyrnasnp
lahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilae
peelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggs
agstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflke

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1jbqF (F:)
gipsetpqaevgptsacgvslgipsetpqaevgptgcphrsgphsakgslekgspedkea
keplwirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkk
fglkcellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaa
avrgyrciivmpekmssekvdvlralgaeivrtptnarfdspeshvgvawrlkneipnsh
ildqyrnasnplahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcrii
gvdpegsilaepeelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarml
iaqegllcggsagstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgflk
eedltekkpwwwhlr

    Sequence, based on observed residues (ATOM records): (download) 
    >1jbqF (F:)
wirpdapsrctwqlgrpasesphhhtapakspkilpdilkkigdtpmvrinkigkkfglk
cellakceffnaggsvkdrislrmiedaerdgtlkpgdtiieptsgntgiglalaaavrg
yrciivmpekmssekvdvlralgaeivrtpteshvgvawrlkneipnshildqyrnasnp
lahydttadeilqqcdgkldmlvasvgtggtitgiarklkekcpgcriigvdpegsilae
peelnqteqttyevegigydfiptvldrtvvdkwfksndeeaftfarmliaqegllcggs
agstvavavkaaqelqegqrcvvilpdsvrnymtkflsdrwmlqkgfl