PDB entry 1it9
View 1it9 on RCSB PDB site
Description: crystal structure of an antigen-binding fragment from a humanized version of the anti-human fas antibody hfe7a
Class: immune system
Keywords: immunoglobulin, fab, anti_fas, agonistic_antibody, apoptosis, antibody_humanization, immune system
Deposited on
2002-01-11, released
2003-02-25
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-12-25, with a file datestamp of
2019-12-20.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: humanized antibody hfe7a, heavy chain
Species: , [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1it9h1, d1it9h2 - Chain 'L':
Compound: humanized antibody hfe7a, light chain
Species: , [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1it9l1, d1it9l2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>1it9H (H:)
qvqlvqsgaevkkpgasvkvsckasgytftsywmqwvkqapgqglewmgeidpsdsytny
nqkfkgkatltvdtststaymelsslrsedtavyycarnrdysnnwyfdvwgegtlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkv
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>1it9L (L:)
eivltqspgtlslspgeratlsckasqsvdydgdsymnwyqqkpgqaprlliyaasnles
gipdrfsgsgsgtdftltisrlepedfavyycqqsnedprtfgqgtkleikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfn