SCOPe 2.08: Structural Classification of Proteins

PDB entry 1iru

View 1iru on RCSB PDB site
Description: Crystal Structure of the mammalian 20S proteasome at 2.75 A resolution
Class: hydrolase
Keywords: 20S proteasome, cell cycle, Immune response, proteolysis, ubiquitin, HYDROLASE
Deposited on 2001-10-24, released 2002-05-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.25
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

Chain '1':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-212)
Domains in SCOPe 2.08: d1iru1_
Chain '2':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1iru2_
Chain 'A':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU
Domains in SCOPe 2.08: d1irua_
Chain 'B':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-232)
Domains in SCOPe 2.08: d1irub_
Chain 'C':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU
Domains in SCOPe 2.08: d1iruc_
Chain 'D':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU
Domains in SCOPe 2.08: d1irud_
Chain 'E':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (Start-240)
Domains in SCOPe 2.08: d1irue_
Chain 'F':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU
Domains in SCOPe 2.08: d1iruf_
Chain 'G':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1irug_
Chain 'H':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1iruh_
Chain 'I':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1irui_
Chain 'J':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P33672 (13-204)
Domains in SCOPe 2.08: d1iruj_
Chain 'K':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1iruk_
Chain 'L':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1irul_
Chain 'M':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-212)
Domains in SCOPe 2.08: d1irum_
Chain 'N':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1irun_
Chain 'O':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU
Domains in SCOPe 2.08: d1iruo_
Chain 'P':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-232)
Domains in SCOPe 2.08: d1irup_
Chain 'Q':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU
Domains in SCOPe 2.08: d1iruq_
Chain 'R':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU
Domains in SCOPe 2.08: d1irur_
Chain 'S':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (Start-240)
Domains in SCOPe 2.08: d1irus_
Chain 'T':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU
Domains in SCOPe 2.08: d1irut_
Chain 'U':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1iruu_
Chain 'V':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1iruv_
Chain 'W':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1iruw_
Chain 'X':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P33672 (13-204)
Domains in SCOPe 2.08: d1irux_
Chain 'Y':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1iruy_
Chain 'Z':
Compound: 20S proteasome
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- PDB 1IRU (0-End)
Domains in SCOPe 2.08: d1iruz_
Heterogens: MG, HOH

PDB Chain Sequences:

Chain '1':
Sequence; same for both SEQRES and ATOM records: (download)

>1iru1 (1:)
rfspyvfnggtilaiagedfaivasdtrlsegfsihtrdspkcykltdktvigcsgfhgd
cltltkiiearlkmykhsnnkamttgaiaamlstilysrrffpyyvyniiggldeegkga
vysfdpvgsyqrdsfkaggsasamlqplldnqvgfknmqnvehvplsldramrlvkdvfi
saaerdvytgdalricivtkegireetvslrkd

Chain '2':
Sequence, based on SEQRES records: (download)

>1iru2 (2:)
tqnpmvtgtsvlgvkfeggvviaadmlgsygslarfrnisrimrvnnstmlgasgdyadf
qylkqvlgqmvideellgdghsyspraihswltramysrrskmnplwntmviggyadges
flgyvdmlgvayeapslatgygaylaqpllrevlekqpvlsqteardlvercmrvlyyrd
arsynrfqtatvtekgveiegplstetnwdiahmisgfe