PDB entry 1iqd
View 1iqd on RCSB PDB site
Description: Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab.
Class: immune system/blood clotting
Keywords: factor viii, c2 domain, antibody, blood coagulation, inhibitor, bo2c11, immune system/blood clotting complex
Deposited on
2001-07-21, released
2001-08-15
The last revision prior to the SCOPe 2.04 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.203
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: human monoclonal bo2c11 fab light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1iqda1, d1iqda2 - Chain 'B':
Compound: human monoclonal bo2c11 fab heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1iqdb1, d1iqdb2 - Chain 'C':
Compound: human factor viii
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1iqdc_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1iqdA (A:)
ialtqspgtlslspgeratlscrasqsfsssylawyqqkpgqaprlliygastratgipd
rfsgsgsgtdftltisrlepedfavyycqkygtsaitfgqgtrleikgtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnr
Sequence, based on observed residues (ATOM records): (download)
>1iqdA (A:)
ialtqspgtlslspgeratlscrasqsfsssylawyqqkpgqaprlliygastratgipd
rfsgsgsgtdftltisrlepedfavyycqkygtsaitfgqgtrleikgtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglvtksfnr
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1iqdB (B:)
qvqlvqsgaevkkpgasvkvsckvsgytltelpvhwvrqapgkglewvgsfdpesgesiy
arefqgsvtmtadtstniaymelsslrsddtavyycavpdpdafdiwgqgtmvtvssast
kgpsvfplapcsrstsestaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtatytcnvdhkpsntkvdkrv
Sequence, based on observed residues (ATOM records): (download)
>1iqdB (B:)
qvqlvqsgaevkkpgasvkvsckvsgytltelpvhwvrqapgkglewvgsfdpesgesiy
arefqgsvtmtadtstniaymelsslrsddtavyycavpdpdafdiwgqgtmvtvssast
kgpsvfplataalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvvtvt
atytcnvdhkpsntkvdkrv
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1iqdC (C:)
csmplgmeskaisdaqitassyftnmfatwspskarlhlqgrsnawrpqvnnpkewlqvd
fqktmkvtgvttqgvkslltsmyvkeflisssqdghqwtlffqngkvkvfqgnqdsftpv
vncldpplltrylrihpqswvhqialrmevlgceaq