PDB entry 1i8l

View 1i8l on RCSB PDB site
Description: human b7-1/ctla-4 co-stimulatory complex
Class: immune system
Keywords: receptors, inhibitory complex, immune system
Deposited on 2001-03-14, released 2001-04-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: t lymphocyte activation antigen cd80
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1i8la1, d1i8la2
  • Chain 'B':
    Compound: t lymphocyte activation antigen cd80
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1i8lb1, d1i8lb2
  • Chain 'C':
    Compound: cytotoxic t-lymphocyte protein 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1i8lc_
  • Chain 'D':
    Compound: cytotoxic t-lymphocyte protein 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1i8ld_
  • Heterogens: NAG, MAN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1i8lA (A:)
vihvtkevkevatlscghnvsveelaqtriywqkekkmvltmmsgdmniwpeyknrtifd
itnnlsivilalrpsdegtyecvvlkyekdafkrehlaevtlsvkadfptpsisdfeipt
snirriicstsggfpephlswlengeelnainttvsqdpetelyavsskldfnmttnhsf
mclikyghlrvnqtfnwnttkqehfpdn

    Sequence, based on observed residues (ATOM records): (download) 
    >1i8lA (A:)
vihvtkevkevatlscghnvsveelaqtriywqkekkmvltmmsgdmniwpeyknrtifd
itnnlsivilalrpsdegtyecvvlkyekdafkrehlaevtlsvkadfptpsisdfeipt
snirriicstsggfpephlswlengeelnainttvsqdpetelyavsskldfnmttnhsf
mclikyghlrvnqtfnwnt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1i8lB (B:)
vihvtkevkevatlscghnvsveelaqtriywqkekkmvltmmsgdmniwpeyknrtifd
itnnlsivilalrpsdegtyecvvlkyekdafkrehlaevtlsvkadfptpsisdfeipt
snirriicstsggfpephlswlengeelnainttvsqdpetelyavsskldfnmttnhsf
mclikyghlrvnqtfnwnttkqehfpdn

    Sequence, based on observed residues (ATOM records): (download) 
    >1i8lB (B:)
vihvtkevkevatlscghnvsveelaqtriywqkekkmvltmmsgdmniwpeyknrtifd
itnnlsivilalrpsdegtyecvvlkyekdafkrehlaevtlsvkadfptpsisdfeipt
snirriicstsggfpephlswlengeelnainttvsqdpetelyavsskldfnmttnhsf
mclikyghlrvnqtfnwnt

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1i8lC (C:)
kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngaqiyvidpe
pcpdsd

    Sequence, based on observed residues (ATOM records): (download) 
    >1i8lC (C:)
mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngaqiyvidpe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1i8lD (D:)
kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngaqiyvidpe
pcpdsd

    Sequence, based on observed residues (ATOM records): (download) 
    >1i8lD (D:)
mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngaqiyvidpe