PDB entry 1i85

View 1i85 on RCSB PDB site
Description: crystal structure of the ctla-4/b7-2 complex
Class: immune system
Keywords: Ig V-type domain, IMMUNE SYSTEM
Deposited on 2001-03-12, released 2001-04-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.217
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: t lymphocyte activation antigen cd86
    Species: Homo sapiens [TaxId:9606]
    Gene: CD86
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42081 (1-109)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d1i85a_
  • Chain 'B':
    Compound: t lymphocyte activation antigen cd86
    Species: Homo sapiens [TaxId:9606]
    Gene: CD86
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1i85b_
  • Chain 'C':
    Compound: cytotoxic t-lymphocyte-associated protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CTLA4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16410
      • see remark 999 (55)
    Domains in SCOPe 2.07: d1i85c_
  • Chain 'D':
    Compound: cytotoxic t-lymphocyte-associated protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: CTLA4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16410
      • see remark 999 (55)
    Domains in SCOPe 2.07: d1i85d_

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1i85A (A:)
    mlkiqayfnetadlpcqfansqnqslselvvfwqdqenlvlnevylgkekfdsvhskymg
    rtsfdsdswtlrlhnlqikdkglyqciihhkkptgmirihqmnselsvla
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1i85B (B:)
    mlkiqayfnetadlpcqfansqnqslselvvfwqdqenlvlnevylgkekfdsvhskymg
    rtsfdsdswtlrlhnlqikdkglyqciihhkkptgmirihqmnselsvla
    

    Sequence, based on observed residues (ATOM records): (download)
    >1i85B (B:)
    lkiqayfnetadlpcqfansqnqslselvvfwqdqenlvlnevylgkekfdsvhskymgr
    tsfdsdswtlrlhnlqikdkglyqciihhkkptgmirihqmnselsvla
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1i85C (C:)
    kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
    tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe
    pcpdsd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1i85C (C:)
    mhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgneltf
    lddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1i85D (D:)
    kamhvaqpavvlassrgiasfvceyaspgkatevrvtvlrqadsqvtevcaatymmgnel
    tflddsictgtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe
    pcpdsd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1i85D (D:)
    mhvaqpavvlassrgiasfvceyaatevrvtvlrqqvtevcaatymmgneltflddsict
    gtssgnqvnltiqglramdtglyickvelmypppyylgigngtqiyvidpe