PDB entry 1i57
View 1i57 on RCSB PDB site
Description: crystal structure of apo human ptp1b (c215s) mutant
Class: hydrolase
Keywords: Substrate-trapping mutant, conformational change, WPD loop, phosphate-binding loop, HYDROLASE
Deposited on
2001-02-26, released
2001-08-08
The last revision prior to the SCOPe 2.03 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.195
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: phospho-tyrosine phosphatase 1b
Species: Homo sapiens [TaxId:9606]
Gene: PTN1_HUMAN
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1i57a_ - Heterogens: MG, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1i57A (A:)
mdykddddklefmemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrd
vspfdhsriklhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvv
mlnrvmekgslkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqet
reilhfhyttwpdfgvpespasflnflfkvresgslspehgpvvvhssagigrsgtfcla
dtclllmdkrkdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvq
dqwkelshed
Sequence, based on observed residues (ATOM records): (download)
>1i57A (A:)
emekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhq
edndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkc
aqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwpd
fgvpespasflnflfkvresgslspehgpvvvhssagigrsgtfcladtclllmdkrkdp
ssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgds