PDB entry 1i3o

View 1i3o on RCSB PDB site
Description: crystal structure of the complex of xiap-bir2 and caspase 3
Class: apoptosis
Keywords: complex, IAP, caspase, Apoptosis
Deposited on 2001-02-15, released 2001-03-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.248
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: caspase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: I39005
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42574
      • engineered (162)
    Domains in SCOPe 2.08: d1i3o.1
  • Chain 'B':
    Compound: caspase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: I39005
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1i3o.1
  • Chain 'C':
    Compound: caspase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: I39005
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42574 (Start-174)
      • engineered (162)
    Domains in SCOPe 2.08: d1i3o.2
  • Chain 'D':
    Compound: caspase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: I39005
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1i3o.2
  • Chain 'E':
    Compound: baculoviral iap repeat-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: U32974
    Database cross-references and differences (RAF-indexed):
    • Uniprot P98170
      • engineered (82)
      • engineered (93)
    Domains in SCOPe 2.08: d1i3oe_
  • Chain 'F':
    Compound: baculoviral iap repeat-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: U32974
    Database cross-references and differences (RAF-indexed):
    • Uniprot P98170
      • engineered (82)
      • engineered (93)
    Domains in SCOPe 2.08: d1i3of_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1i3oA (A:)
mentensvdsksiknlepkiihgsesmdsgisldnsykmdypemglciiinnknfhkstg
mtsrsgtdvdaanlretfrnlkyevrnkndltreeivelmrdvskedhskrssfvcvlls
hgeegiifgtngpvdlkkitnffrgdrcrsltgkpklfiiqaargteldcgietd

    Sequence, based on observed residues (ATOM records): (download) 
    >1i3oA (A:)
sldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndl
treeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsl
tgkpklfiiqaargteldcgiet

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1i3oB (B:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1i3oB (B:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfy

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1i3oC (C:)
mentensvdsksiknlepkiihgsesmdsgisldnsykmdypemglciiinnknfhkstg
mtsrsgtdvdaanlretfrnlkyevrnkndltreeivelmrdvskedhskrssfvcvlls
hgeegiifgtngpvdlkkitnffrgdrcrsltgkpklfiiqaargteldcgietd

    Sequence, based on observed residues (ATOM records): (download) 
    >1i3oC (C:)
sldnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndl
treeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsl
tgkpklfiiqaargteldcgietd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1i3oD (D:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyhlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1i3oD (D:)
sgvdddmachkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklefmhi
ltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfy

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1i3oE (E:)
gshmrdhfaldrpsethadyllrtgqvvdisdtiyprnpamyseearlksfqnwpdyahl
tprelasaglyytgigdqvqcfacggklknwepgdrawsehrrhfpncffvlgrnlnirs
e

    Sequence, based on observed residues (ATOM records): (download) 
    >1i3oE (E:)
faldrpsethadyllrtgqvvdisdtiyprnpamyseearlksfqnwpdyahltprelas
aglyytgigdqvqcfacggklknwepgdrawsehrrhfpncffvlgrnlni

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1i3oF (F:)
gshmrdhfaldrpsethadyllrtgqvvdisdtiyprnpamyseearlksfqnwpdyahl
tprelasaglyytgigdqvqcfacggklknwepgdrawsehrrhfpncffvlgrnlnirs
e

    Sequence, based on observed residues (ATOM records): (download) 
    >1i3oF (F:)
thadyllrtgqvvdisdtiyprnpamyseearlksltprelasaglyytgigdqvqcfac
ggklknwepgdrawsehrrhfpncffvlgrnln