PDB entry 1hw5

View 1hw5 on RCSB PDB site
Description: the cap/crp variant t127l/s128a
Class: gene regulation
Keywords: cAMP Receptor Protein, Catabolite Activator Protein (CAP) Transcription, Allostery, cAMP, cyclic AMP Mutant, GENE REGULATION
Deposited on 2001-01-09, released 2001-01-17
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.82 Å
R-factor: 0.228
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Catabolite gene activator
    Species: Escherichia coli [TaxId:562]
    Gene: CRP/CAP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0ACJ8
      • engineered (127-128)
    Domains in SCOPe 2.03: d1hw5a1, d1hw5a2
  • Chain 'B':
    Compound: Catabolite gene activator
    Species: Escherichia coli [TaxId:562]
    Gene: CRP/CAP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0ACJ8
      • engineered (127-128)
    Domains in SCOPe 2.03: d1hw5b1, d1hw5b2
  • Heterogens: CMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hw5A (A:)
mvlgkpqtdptlewflshchihkypskstlihqgekaetlyyivkgsvavlikdeegkem
ilsylnqgdfigelglfeegqersawvraktacevaeisykkfrqliqvnpdilmrlsaq
marrlqvlaekvgnlafldvtgriaqtllnlakqpdamthpdgmqikitrqeigqivgcs
retvgrilkmledqnlisahgktivvygtr

    Sequence, based on observed residues (ATOM records): (download) 
    >1hw5A (A:)
vlgkpqtdptlewflshchihkypskstlihqgekaetlyyivkgsvavlikdeegkemi
lsylnqgdfigelglfeegqersawvraktacevaeisykkfrqliqvnpdilmrlsaqm
arrlqvlaekvgnlafldvtgriaqtllnlakqpdamthpdgmqikitrqeigqivgcsr
etvgrilkmledqnlisahgktivvygt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hw5B (B:)
mvlgkpqtdptlewflshchihkypskstlihqgekaetlyyivkgsvavlikdeegkem
ilsylnqgdfigelglfeegqersawvraktacevaeisykkfrqliqvnpdilmrlsaq
marrlqvlaekvgnlafldvtgriaqtllnlakqpdamthpdgmqikitrqeigqivgcs
retvgrilkmledqnlisahgktivvygtr

    Sequence, based on observed residues (ATOM records): (download) 
    >1hw5B (B:)
vlgkpqtdptlewflshchihkypskstlihqgekaetlyyivkgsvavlikdeegkemi
lsylnqgdfigelglfeegqersawvraktacevaeisykkfrqliqvnpdilmrlsaqm
arrlqvlaekvgnlafldvtgriaqtllnlakqpdamthpdgmqikitrqeigqivgcsr
etvgrilkmledqnlisahgktivv