PDB entry 1hv5

View 1hv5 on RCSB PDB site
Description: crystal structure of the stromelysin-3 (mmp-11) catalytic domain complexed with a phosphinic inhibitor
Class: hydrolase
Keywords: stromelysin-3, inhibition, phosphinic inhibitor, hydrolase
Deposited on 2001-01-08, released 2001-03-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.218
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: stromelysin 3
    Species: Mus musculus [TaxId:10090]
    Gene: STRO3 (101-264)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hv5a_
  • Chain 'B':
    Compound: stromelysin 3
    Species: Mus musculus [TaxId:10090]
    Gene: STRO3 (101-264)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hv5b_
  • Chain 'C':
    Compound: stromelysin 3
    Species: Mus musculus [TaxId:10090]
    Gene: STRO3 (101-264)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hv5c_
  • Chain 'D':
    Compound: stromelysin 3
    Species: Mus musculus [TaxId:10090]
    Gene: STRO3 (101-264)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hv5d_
  • Chain 'E':
    Compound: stromelysin 3
    Species: Mus musculus [TaxId:10090]
    Gene: STRO3 (101-264)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hv5e_
  • Chain 'F':
    Compound: stromelysin 3
    Species: Mus musculus [TaxId:10090]
    Gene: STRO3 (101-264)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hv5f_
  • Heterogens: ZN, CA, CPS, RXP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hv5A (A:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlygrpq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hv5A (A:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlyg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hv5B (B:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlygrpq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hv5B (B:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlygrp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1hv5C (C:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlygrpq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hv5C (C:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlyg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1hv5D (D:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlygrpq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hv5D (D:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlyg

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1hv5E (E:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlygrpq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1hv5F (F:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlygrpq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hv5F (F:)
mfvlsggrwektdltyrilrfpwqlvreqvrqtvaealqvwsevtpltftevhegradim
idfarywhgdnlpfdgpggilahaffpkthregdvhfdydetwtigdnqgtdllqvaahe
fghvlglqhttaakalmspfytfryplslspddrrgiqhlyg