PDB entry 1hr7

View 1hr7 on RCSB PDB site
Description: Yeast Mitochondrial Processing Peptidase beta-E73Q Mutant
Class: hydrolase
Keywords: HxxEH zinc-binding motif, HYDROLASE
Deposited on 2000-12-21, released 2001-07-11
The last revision prior to the SCOP 1.75 freeze date was dated 2008-05-06, with a file datestamp of 2008-05-02.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.243
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mitochondrial processing peptidase alpha subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11914 (0-End)
      • see remark 999 (163)
      • see remark 999 (203)
    Domains in SCOP 1.75: d1hr7a1, d1hr7a2
  • Chain 'B':
    Compound: mitochondrial processing peptidase beta subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10507 (Start-442)
      • engineered (53)
      • see remark 999 (64)
      • see remark 999 (330)
    Domains in SCOP 1.75: d1hr7b1, d1hr7b2
  • Chain 'C':
    Compound: mitochondrial processing peptidase alpha subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11914
      • see remark 999 (163)
      • see remark 999 (203)
    Domains in SCOP 1.75: d1hr7c1, d1hr7c2
  • Chain 'D':
    Compound: mitochondrial processing peptidase beta subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10507 (Start-442)
      • engineered (53)
      • see remark 999 (64)
      • see remark 999 (330)
    Domains in SCOP 1.75: d1hr7d1, d1hr7d2
  • Chain 'E':
    Compound: mitochondrial processing peptidase alpha subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11914 (0-End)
      • see remark 999 (163)
      • see remark 999 (203)
    Domains in SCOP 1.75: d1hr7e1, d1hr7e2
  • Chain 'F':
    Compound: mitochondrial processing peptidase beta subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10507 (Start-442)
      • engineered (53)
      • see remark 999 (64)
      • see remark 999 (330)
    Domains in SCOP 1.75: d1hr7f1, d1hr7f2
  • Chain 'G':
    Compound: mitochondrial processing peptidase alpha subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11914 (0-End)
      • see remark 999 (163)
      • see remark 999 (203)
    Domains in SCOP 1.75: d1hr7g1, d1hr7g2
  • Chain 'H':
    Compound: mitochondrial processing peptidase beta subunit
    Species: Saccharomyces cerevisiae
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10507 (Start-442)
      • engineered (53)
      • see remark 999 (64)
      • see remark 999 (330)
    Domains in SCOP 1.75: d1hr7h1, d1hr7h2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1hr7A (A:)
    artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
    hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
    eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
    fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
    pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
    encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
    lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
    nagngkgratvvmqgdrgsfgdvenvlkayglgnsssskndspkkkgwfhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hr7A (A:)
    artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
    hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
    eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
    fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
    pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
    encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
    lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
    nagngkgratvvmqgdrgsfgdvenvlkayglgnsss
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1hr7B (B:)
    asqipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkg
    tqnrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsa
    iererdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyi
    tknykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfik
    entlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngsl
    ansymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaq
    lkaalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpv
    smvalgntstvpnvsyieeklnq
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hr7B (B:)
    pgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkgtqnr
    pqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsaiere
    rdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyitkny
    kgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfikentl
    ptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngslansy
    msfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaqlkaa
    lllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpvsmva
    lgntstvpnvsyieeklnq
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1hr7C (C:)
    artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
    hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
    eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
    fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
    pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
    encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
    lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
    nagngkgratvvmqgdrgsfgdvenvlkayglgnsssskndspkkkgwfhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hr7C (C:)
    tdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkstehv
    egramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelqeq
    klsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnkfy
    tpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnlpe
    lfhiqigfeglpidhpdiyalatlqtllgggggmysrlythvlnqyyfvencvafnhsys
    dsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknqlkssllmnles
    klveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvnnagngkgratv
    vmqgdrgsfgdvenvlkayglgns
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1hr7D (D:)
    asqipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkg
    tqnrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsa
    iererdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyi
    tknykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfik
    entlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngsl
    ansymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaq
    lkaalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpv
    smvalgntstvpnvsyieeklnq
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hr7D (D:)
    qipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkgtq
    nrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsaie
    rerdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyitk
    nykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfiken
    tlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngslan
    symsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaqlk
    aalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpvsm
    valgntstvpnvsyieeklnq
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1hr7E (E:)
    artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
    hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
    eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
    fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
    pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
    encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
    lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
    nagngkgratvvmqgdrgsfgdvenvlkayglgnsssskndspkkkgwfhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hr7E (E:)
    artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
    hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
    eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
    fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
    pelfhiqigfeglpidhpdiyalatlqtllggggskgmysrlythvlnqyyfvencvafn
    hsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknqlkssllm
    nlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvnnagngkg
    ratvvmqgdrgsfgdvenvlkayglgns
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1hr7F (F:)
    asqipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkg
    tqnrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsa
    iererdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyi
    tknykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfik
    entlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngsl
    ansymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaq
    lkaalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpv
    smvalgntstvpnvsyieeklnq
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hr7F (F:)
    ipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkgtqn
    rpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsaier
    erdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyitkn
    ykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfikent
    lptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngslans
    ymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaqlka
    alllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpvsmv
    algntstvpnvsyieeklnq
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1hr7G (G:)
    artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
    hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
    eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
    fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
    pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
    encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
    lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
    nagngkgratvvmqgdrgsfgdvenvlkayglgnsssskndspkkkgwfhhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hr7G (G:)
    artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
    hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
    eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
    fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
    pelfhiqigfeglpidhpdiyalatlqtllggggggpgkgmysrlythvlnqyyfvencv
    afnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknqlkss
    llmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvnnagn
    gkgratvvmqgdrgsfgdvenvlkayglgn
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1hr7H (H:)
    asqipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkg
    tqnrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsa
    iererdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyi
    tknykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfik
    entlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngsl
    ansymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaq
    lkaalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpv
    smvalgntstvpnvsyieeklnq
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hr7H (H:)
    ipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkgtqn
    rpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsaier
    erdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyitkn
    ykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfikent
    lptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngslans
    ymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaqlka
    alllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpvsmv
    algntstvpnvsyieeklnq