PDB entry 1hr7

View 1hr7 on RCSB PDB site
Description: Yeast Mitochondrial Processing Peptidase beta-E73Q Mutant
Class: hydrolase
Keywords: HxxEH zinc-binding motif, HYDROLASE
Deposited on 2000-12-21, released 2001-07-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-06-23, with a file datestamp of 2009-06-19.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.243
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mitochondrial processing peptidase alpha subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11914 (0-End)
      • see remark 999 (163)
      • see remark 999 (203)
    Domains in SCOPe 2.08: d1hr7a1, d1hr7a2
  • Chain 'B':
    Compound: mitochondrial processing peptidase beta subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10507 (Start-442)
      • engineered (53)
      • see remark 999 (64)
      • see remark 999 (330)
    Domains in SCOPe 2.08: d1hr7b1, d1hr7b2
  • Chain 'C':
    Compound: mitochondrial processing peptidase alpha subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11914
      • see remark 999 (163)
      • see remark 999 (203)
    Domains in SCOPe 2.08: d1hr7c1, d1hr7c2
  • Chain 'D':
    Compound: mitochondrial processing peptidase beta subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10507 (Start-442)
      • engineered (53)
      • see remark 999 (64)
      • see remark 999 (330)
    Domains in SCOPe 2.08: d1hr7d1, d1hr7d2
  • Chain 'E':
    Compound: mitochondrial processing peptidase alpha subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11914 (0-End)
      • see remark 999 (163)
      • see remark 999 (203)
    Domains in SCOPe 2.08: d1hr7e1, d1hr7e2
  • Chain 'F':
    Compound: mitochondrial processing peptidase beta subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10507 (Start-442)
      • engineered (53)
      • see remark 999 (64)
      • see remark 999 (330)
    Domains in SCOPe 2.08: d1hr7f1, d1hr7f2
  • Chain 'G':
    Compound: mitochondrial processing peptidase alpha subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11914 (0-End)
      • see remark 999 (163)
      • see remark 999 (203)
    Domains in SCOPe 2.08: d1hr7g1, d1hr7g2
  • Chain 'H':
    Compound: mitochondrial processing peptidase beta subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10507 (Start-442)
      • engineered (53)
      • see remark 999 (64)
      • see remark 999 (330)
    Domains in SCOPe 2.08: d1hr7h1, d1hr7h2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hr7A (A:)
artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
nagngkgratvvmqgdrgsfgdvenvlkayglgnsssskndspkkkgwfhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1hr7A (A:)
artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
nagngkgratvvmqgdrgsfgdvenvlkayglgnsss

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hr7B (B:)
asqipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkg
tqnrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsa
iererdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyi
tknykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfik
entlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngsl
ansymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaq
lkaalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpv
smvalgntstvpnvsyieeklnq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hr7B (B:)
pgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkgtqnr
pqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsaiere
rdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyitkny
kgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfikentl
ptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngslansy
msfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaqlkaa
lllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpvsmva
lgntstvpnvsyieeklnq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1hr7C (C:)
artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
nagngkgratvvmqgdrgsfgdvenvlkayglgnsssskndspkkkgwfhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1hr7C (C:)
tdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkstehv
egramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelqeq
klsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnkfy
tpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnlpe
lfhiqigfeglpidhpdiyalatlqtllgggggmysrlythvlnqyyfvencvafnhsys
dsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknqlkssllmnles
klveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvnnagngkgratv
vmqgdrgsfgdvenvlkayglgns

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1hr7D (D:)
asqipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkg
tqnrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsa
iererdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyi
tknykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfik
entlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngsl
ansymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaq
lkaalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpv
smvalgntstvpnvsyieeklnq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hr7D (D:)
qipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkgtq
nrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsaie
rerdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyitk
nykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfiken
tlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngslan
symsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaqlk
aalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpvsm
valgntstvpnvsyieeklnq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1hr7E (E:)
artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
nagngkgratvvmqgdrgsfgdvenvlkayglgnsssskndspkkkgwfhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1hr7E (E:)
artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
pelfhiqigfeglpidhpdiyalatlqtllggggskgmysrlythvlnqyyfvencvafn
hsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknqlkssllm
nlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvnnagngkg
ratvvmqgdrgsfgdvenvlkayglgns

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1hr7F (F:)
asqipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkg
tqnrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsa
iererdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyi
tknykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfik
entlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngsl
ansymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaq
lkaalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpv
smvalgntstvpnvsyieeklnq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hr7F (F:)
ipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkgtqn
rpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsaier
erdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyitkn
ykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfikent
lptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngslans
ymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaqlka
alllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpvsmv
algntstvpnvsyieeklnq

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1hr7G (G:)
artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
pelfhiqigfeglpidhpdiyalatlqtllggggsfsaggpgkgmysrlythvlnqyyfv
encvafnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknq
lkssllmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvn
nagngkgratvvmqgdrgsfgdvenvlkayglgnsssskndspkkkgwfhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1hr7G (G:)
artdnfklsslanglkvatsntpghfsalglyidagsrfegrnlkgcthildrlafkste
hvegramaetlellggnyqctssrenlmyqasvfnqdvgkmlqlmsetvrfpkiteqelq
eqklsaeyeidevwmkpelvlpellhtaaysgetlgsplicprglipsiskyylldyrnk
fytpentvaafvgvphekaleltgkylgdwqsthppitkkvaqytggescippapvfgnl
pelfhiqigfeglpidhpdiyalatlqtllggggggpgkgmysrlythvlnqyyfvencv
afnhsysdsgifgislscipqaapqaveviaqqmyntfankdlrltedevsraknqlkss
llmnlesklveledmgrqvlmhgrkipvnemiskiedlkpddisrvaemiftgnvnnagn
gkgratvvmqgdrgsfgdvenvlkayglgn

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1hr7H (H:)
asqipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkg
tqnrpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsa
iererdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyi
tknykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfik
entlptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngsl
ansymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaq
lkaalllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpv
smvalgntstvpnvsyieeklnq

    Sequence, based on observed residues (ATOM records): (download) 
    >1hr7H (H:)
ipgtrtsklpngltiateyipntssatvgifvdagsraenvknngtahflqhlafkgtqn
rpqqgieleienigshlnaytsrentvyyakslqedipkavdilsdiltksvldnsaier
erdviireseevdkmydevvfdhlheitykdqplgrtilgpikniksitrtdlkdyitkn
ykgdrmvlagagavdheklvqyaqkyfghvpksespvplgsprgplpvfcrgerfikent
lptthiaialegvswsapdyfvalatqaivgnwdraigtgtnspsplavaasqngslans
ymsfstsyadsglwgmyivtdsnehnvrlivneilkewkriksgkisdaevnrakaqlka
alllsldgstaivedigrqvvttgkrlspeevfeqvdkitkddiimwanyrlqnkpvsmv
algntstvpnvsyieeklnq