PDB entry 1h2v

View 1h2v on RCSB PDB site
Description: structure of the human nuclear cap-binding-complex (cbc)
Class: nuclear protein
Keywords: cap-binding-complex, rnp domain, mif4g domain, RNA maturation, RNA export, nuclear protein, RNA-binding
Deposited on 2002-08-16, released 2002-10-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.212
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: 80 kda nuclear cap binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q09161 (Start-770)
      • engineered mutation (459)
    Domains in SCOPe 2.06: d1h2vc1, d1h2vc2, d1h2vc3
  • Chain 'Z':
    Compound: 20 kda nuclear cap binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1h2vz_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1h2vC (C:)
ktsdanetedhleslickvgeksacslesnleglagvleadlpnykskilrllctvarll
pekltiyttlvgllnarnynfggefveamirqlkeslkannyneavylvrflsdlvnchv
iaapsmvamfenfvsvtqeedvpqvrrdwyvyaflsslpwvgkelyekkdaemdrifant
esylkrrqkthvpmlqvwtadkphpqeeyldclwaqiqklkkdrwqerhilrpylafdsi
lcealqhnlppftppphtedsvypmprvifrmfdytddpegpvmpgshsverfvieenlh
ciikshwkerktcaaqlvsypgknkiplnyhivevifaelfqlpapphidvmyttlliel
cklqpgslpqvlaqatemlymrldtmnttcvdrfinwfshhlsnfqfrwswedwsdclsq
dpespkpkfvrevlekcmrlsyhqrildivpptfsalcpsnptciykygdessnslpghs
valclavafkskatndeifsilkdvpnpnqdddddegfsfnplkievfvqtllhlaaksf
shsfsalakfhevfktlaesdegklhvlrvmfevwrnhpqmiavlvdkmirtqivdcaav
anwifsselsrdftrlfvweilhstirkmnkhvlkiqkeleeakeklarqhkrrsddddr
ssdrkdgvleeqierlqekvesaqseqknlflvifqrfimiltehlvrcetdgtsvltpw
ykncierlqqiflqhhqiiqqymvtlenllftaeldphilavfqqfcalqa

    Sequence, based on observed residues (ATOM records): (download) 
    >1h2vC (C:)
dhleslickvgeksacslesnleglagvleadlpnykskilrllctvarllpekltiytt
lvgllnarnynfggefveamirqlkeslkannyneavylvrflsdlvnchviaapsmvam
fenfvsvtqeedvpqvrrdwyvyaflsslpwvgkelyekkdaemdrifantesylkrrqk
thvpmlqvwtadkphpqeeyldclwaqiqklkkdrwqerhilrpylafdsilcealqhnl
ppftppphtedsvypmprvifrmfdytddpegpvmpgshsverfvieenlhciikshwke
rktcaaqlvsypgknkiplnyhivevifaelfqlpapphidvmyttllielcklqpgslp
qvlaqatemlymrldtmnttcvdrfinwfshhlsnfqfrwswedwsdclsqdpespkpkf
vrevlekcmrlsyhqrildivpptfsalcpsnptciykygdessnslpghsvalclavaf
kskatndeifsilkdvpnfnplkievfvqtllhlaaksfshsfsalakfhevfktlaesd
egklhvlrvmfevwrnhpqmiavlvdkmirtqivdcaavanwifsselsrdftrlfvwei
lhstirkmnkhvlkiqkeleeakierlqekvesaqseqknlflvifqrfimiltehlvrc
etdgtsvltpwykncierlqqiflqhhqiiqqymvtlenllftaeldphilavfqqfcal
qa

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >1h2vZ (Z:)
msggllkalrsdsyvelsqyrdqhfrgdneeqekllkksctlyvgnlsfytteeqiyelf
sksgdikkiimgldkmkktacgfcfveyysradaenamryingtrlddriirtdwdagfk
egrqygrgrsggqvrdeyrqdydagrggygklaqnq

    Sequence, based on observed residues (ATOM records): (download) 
    >1h2vZ (Z:)
ekllkksctlyvgnlsfytteeqiyelfsksgdikkiimgldkmkktacgfcfveyysra
daenamryingtrlddriirtdwdagfkegrqy