PDB entry 1h0v

View 1h0v on RCSB PDB site
Description: human cyclin dependent protein kinase 2 in complex with the inhibitor 2-amino-6-[(r)-pyrrolidino-5'-yl]methoxypurine
Class: transferase
Keywords: transferase, drug metabolism, mycobacteria, isoniazid, arylamine n-acetyltransferase, nat, serine/threonine -protein kinase, ATP-binding, cell cycle, cell division, mitosis
Deposited on 2002-06-27, released 2003-06-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.158
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1h0va_
  • Heterogens: UN4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1h0vA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1h0vA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirvpstaireisllkelnhpnivkll
    dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
    lkpqnllintegaikladfglarafgvpvrtevvtlwyrapeillgckyystavdiwslg
    cifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfsk
    vvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl