PDB entry 1h08

View 1h08 on RCSB PDB site
Description: cdk2 in complex with a disubstituted 2, 4-bis anilino pyrimidine cdk4 inhibitor
Class: transferase
Keywords: serine/threonine-protein kinase,mitosis,transferase
Deposited on 2002-06-11, released 2003-07-11
The last revision prior to the SCOP 1.75 freeze date was dated 2003-09-04, with a file datestamp of 2007-07-06.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.213
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1h08a_
  • Heterogens: ACE, BYP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1h08A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >1h08A (A:)
menfqkvekigegtygvvykarnkltgevvalkkivpstaireisllkelnhpnivklld
vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
kpqnllintegaikladfglarafghevvtlwyrapeillgckyystavdiwslgcifae
mvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppl
dedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl