PDB entry 1h06

View 1h06 on RCSB PDB site
Description: cdk2 in complex with a disubstituted 4, 6-bis anilino pyrimidine cdk4 inhibitor
Class: transferase
Keywords: serine/threonine-protein kinase,mitosis,transferase
Deposited on 2002-06-11, released 2003-07-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2004-05-04, with a file datestamp of 2007-04-25.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: 0.223
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • PDB 1H06
    • Uniprot P24941 (0-297)
    Domains in SCOPe 2.07: d1h06a_
  • Heterogens: 3FP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1h06A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1h06A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirltaireisllkelnhpnivklldv
    ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
    pqnllintegaikladfglarvvtlwyrapeillgckyystavdiwslgcifaemvtrra
    lfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrs
    llsqmlhydpnkrisakaalahpffqdvtkpvphlrl