PDB entry 1h00

View 1h00 on RCSB PDB site
Description: cdk2 in complex with a disubstituted 4, 6-bis anilino pyrimidine cdk4 inhibitor
Class: transferase
Keywords: serine/threonine-protein kinase, mitosis, transferase
Deposited on 2002-06-10, released 2003-07-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.208
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1H00
    • Uniprot P24941 (0-297)
    Domains in SCOPe 2.07: d1h00a_
  • Heterogens: FAP, FCP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1h00A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1h00A (A:)
    menfqkvekigeygvvykarnkltgevvalkkivpstaireisllkelnhpnivklldvi
    htenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkp
    qnllintegaikladfglaraevvtlwyrapeillgckyystavdiwslgcifaemvtrr
    alfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgr
    sllsqmlhydpnkrisakaalahpffqdvtkpvphlrl