PDB entry 1gua

View 1gua on RCSB PDB site
Description: human rap1a, residues 1-167, double mutant (e30d,k31e) complexed with gppnhp and the ras-binding-domain of human c-raf1, residues 51-131
Class: complex (GTP-binding/ATP-binding)
Keywords: oncogene protein/kinase/effector protein GTP-binding-protein, complex (GTP-binding/ATP-binding)
Deposited on 1996-06-18, released 1997-01-11
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.22
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: rap1a
    Species: Homo sapiens [TaxId:9606]
    Gene: HUMAN C-RAF1 GENE RESIDUES 51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62834 (0-166)
      • engineered (29-30)
    Domains in SCOPe 2.06: d1guaa_
  • Chain 'B':
    Compound: c-raf1
    Species: Homo sapiens [TaxId:9606]
    Gene: HUMAN C-RAF1 GENE RESIDUES 51
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1guab_
  • Heterogens: MG, CA, GNP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1guaA (A:)
    mreyklvvlgsggvgksaltvqfvqgifvdeydptiedsyrkqvevdcqqcmleildtag
    teqftamrdlymkngqgfalvysitaqstfndlqdlreqilrvkdtedvpmilvgnkcdl
    edervvgkeqgqnlarqwcncaflessakskinvneifydlvrqinr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1guaB (B:)
    psktsntirvflpnkqrtvvnvrngmslhdclmkalkvrglqpeccavfrllhehkgkka
    rldwntdaasligeelqvdfl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1guaB (B:)
    ntirvflpnkqrtvvnvrngmslhdclmkalkvrglqpeccavfrllhehkgkkarldwn
    tdaasligeelqvdfl