PDB entry 1gkd

View 1gkd on RCSB PDB site
Description: mmp9 active site mutant-inhibitor complex
Class: hydrolase
Keywords: matrix metalloprotease, hydrolase, glycoprotein
Deposited on 2001-08-10, released 2002-05-16
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.212
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 92 kda type IV collagenase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • PDB 1GKD
      • engineered mutation (121)
    • Uniprot P14780 (110-162)
    Domains in SCOP 1.75: d1gkda_
  • Chain 'B':
    Compound: 92 kda type IV collagenase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • PDB 1GKD
      • engineered mutation (121)
    • Uniprot P14780 (110-162)
    Domains in SCOP 1.75: d1gkdb_
  • Heterogens: CA, ZN, STN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1gkdA (A:)
mfqtfegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdad
iviqfgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaa
hqfghalgldhssvpealmypmyrftegpplhkddvngirhly

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkdA (A:)
fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfg
halgldhssvpealmypmyrftegpplhkddvngirhly

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1gkdB (B:)
mfqtfegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdad
iviqfgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaa
hqfghalgldhssvpealmypmyrftegpplhkddvngirhly

    Sequence, based on observed residues (ATOM records): (download) 
    >1gkdB (B:)
lkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviqfgva
ehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfghalg
ldhssvpealmypmyrftegpplhkddvngirhly