PDB entry 1gii

View 1gii on RCSB PDB site
Description: human cyclin dependent kinase 2 complexed with the cdk4 inhibitor
Class: transferase
Keywords: protein kinase, cell cycle, inhibition, TRANSFERASE
Deposited on 2001-02-06, released 2002-02-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.202
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24941 (0-297)
      • engineered (81-82)
      • engineered (88)
    Domains in SCOPe 2.07: d1giia_
  • Heterogens: 1PU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1giiA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfehvhqdlktfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1giiA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkivpstaireisllkelnhpnivklld
    vihtenklylvfehvhqdlktfmdasaltgiplpliksylfqllqglafchshrvlhrdl
    kpqnllintegaikladfglarafvtlwyrapeillgckyystavdiwslgcifaemvtr
    ralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedg
    rsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl