PDB entry 1g5s

View 1g5s on RCSB PDB site
Description: crystal structure of human cyclin dependent kinase 2 (cdk2) in complex with the inhibitor h717
Class: cell cycle/transferase
Keywords: protein-inhibitor complex
Deposited on 2000-11-02, released 2001-11-02
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.61 Å
R-factor: 0.201
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1g5sa_
  • Heterogens: I17, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1g5sA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1g5sA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirstaireisllkelnhpnivklldv
    ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
    pqnllintegaikladfglvvtlwyrapeillgckyystavdiwslgcifaemvtrralf
    pgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsll
    sqmlhydpnkrisakaalahpffqdvtkpvphlrl