PDB entry 1ftn

View 1ftn on RCSB PDB site
Description: crystal structure of the human rhoa/GDP complex
Class: proto-oncogene
Keywords: proto-oncogene, GTP-binding, prenylation, lipoprotein, small p-protein
Deposited on 1997-03-13, released 1998-03-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.304
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: transforming protein rhoa (h12)
    Species: Homo sapiens [TaxId:9606]
    Gene: SYNTHETIC HUMAN RHOA GENE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61586
      • engineered (24)
    Domains in SCOPe 2.07: d1ftna_
  • Heterogens: MG, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1ftnA (A:)
    maairkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdt
    agqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkd
    lrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq
    arrgkkksgclvl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ftnA (A:)
    irkklvivgdgacgktcllivnskdqfpevyvptvfenyvadievdgkqvelalwdtagq
    edydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlrn
    dehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalq