PDB entry 1fqv

View 1fqv on RCSB PDB site
Description: Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex
Class: ligase
Keywords: Skp1, Skp2, F-box, LRR, leucine-rich repeat, SCF, ubiquitin, E3, ubiquitin protein ligase
Deposited on 2000-09-06, released 2000-11-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.275
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: skp2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqva1, d1fqva2
  • Chain 'B':
    Compound: skp1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvb1, d1fqvb2
  • Chain 'C':
    Compound: skp2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvc1, d1fqvc2
  • Chain 'D':
    Compound: skp1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvd1, d1fqvd2
  • Chain 'E':
    Compound: skp2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqve1, d1fqve2
  • Chain 'F':
    Compound: skp1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvf1, d1fqvf2
  • Chain 'G':
    Compound: skp2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvg1, d1fqvg2
  • Chain 'H':
    Compound: skp1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvh1, d1fqvh2
  • Chain 'I':
    Compound: skp2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvi1, d1fqvi2
  • Chain 'J':
    Compound: skp1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvj1, d1fqvj2
  • Chain 'K':
    Compound: skp2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvk1, d1fqvk2
  • Chain 'L':
    Compound: skp1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvl1, d1fqvl2
  • Chain 'M':
    Compound: skp2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvm1, d1fqvm2
  • Chain 'N':
    Compound: skp1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvn1, d1fqvn2
  • Chain 'O':
    Compound: skp2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvo1, d1fqvo2
  • Chain 'P':
    Compound: skp1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1fqvp1, d1fqvp2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fqvA (A:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlh
pdvtgrllsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcskl
qnlsleglrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfd
ftekhvqvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcf
qeffqlnylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqi
ncshfttiarptignkknqeiwgikcrltlqkpscl

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvA (A:)
vswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlhpdvtgr
llsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcsklqnlsle
glrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfdftekhv
qvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcfqeffql
nylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqincshft
tiarptignkknqeiwgikcrltlq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1fqvB (B:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvB (B:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikn
dfteeeeaqvrkenqwc

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1fqvC (C:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlh
pdvtgrllsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcskl
qnlsleglrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfd
ftekhvqvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcf
qeffqlnylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqi
ncshfttiarptignkknqeiwgikcrltlqkpscl

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvC (C:)
vswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlhpdvtgr
llsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcsklqnlsle
glrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfdftekhv
qvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcfqeffql
nylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqincshft
tiarptignkknqeiwgikcrltlq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1fqvD (D:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvD (D:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikn
dfteeeeaqvrkenqwc

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1fqvE (E:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlh
pdvtgrllsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcskl
qnlsleglrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfd
ftekhvqvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcf
qeffqlnylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqi
ncshfttiarptignkknqeiwgikcrltlqkpscl

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvE (E:)
vswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlhpdvtgr
llsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcsklqnlsle
glrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfdftekhv
qvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcfqeffql
nylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqincshft
tiarptignkknqeiwgikcrltlq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1fqvF (F:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvF (F:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikn
dfteeeeaqvrkenqwc

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1fqvG (G:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlh
pdvtgrllsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcskl
qnlsleglrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfd
ftekhvqvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcf
qeffqlnylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqi
ncshfttiarptignkknqeiwgikcrltlqkpscl

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvG (G:)
vswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlhpdvtgr
llsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcsklqnlsle
glrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfdftekhv
qvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcfqeffql
nylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqincshft
tiarptignkknqeiwgikcrltlq

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1fqvH (H:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvH (H:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikn
dfteeeeaqvrkenqwc

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1fqvI (I:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlh
pdvtgrllsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcskl
qnlsleglrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfd
ftekhvqvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcf
qeffqlnylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqi
ncshfttiarptignkknqeiwgikcrltlqkpscl

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvI (I:)
vswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlhpdvtgr
llsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcsklqnlsle
glrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfdftekhv
qvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcfqeffql
nylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqincshft
tiarptignkknqeiwgikcrltlq

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1fqvJ (J:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvJ (J:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikn
dfteeeeaqvrkenqwc

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1fqvK (K:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlh
pdvtgrllsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcskl
qnlsleglrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfd
ftekhvqvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcf
qeffqlnylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqi
ncshfttiarptignkknqeiwgikcrltlqkpscl

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvK (K:)
vswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlhpdvtgr
llsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcsklqnlsle
glrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfdftekhv
qvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcfqeffql
nylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqincshft
tiarptignkknqeiwgikcrltlq

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1fqvL (L:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvL (L:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikn
dfteeeeaqvrkenqwc

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >1fqvM (M:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlh
pdvtgrllsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcskl
qnlsleglrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfd
ftekhvqvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcf
qeffqlnylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqi
ncshfttiarptignkknqeiwgikcrltlqkpscl

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvM (M:)
vswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlhpdvtgr
llsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcsklqnlsle
glrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfdftekhv
qvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcfqeffql
nylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqincshft
tiarptignkknqeiwgikcrltlq

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >1fqvN (N:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvN (N:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikn
dfteeeeaqvrkenqwc

  • Chain 'O':
    Sequence, based on SEQRES records: (download) 
    >1fqvO (O:)
renfpgvswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlh
pdvtgrllsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcskl
qnlsleglrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfd
ftekhvqvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcf
qeffqlnylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqi
ncshfttiarptignkknqeiwgikcrltlqkpscl

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvO (O:)
vswdslpdelllgifsclclpellkvsgvckrwyrlasdeslwqtldltgknlhpdvtgr
llsqgviafrcprsfmdqplaehfspfrvqhmdlsnsvievstlhgilsqcsklqnlsle
glrlsdpivntlaknsnlvrlnlsgcsgfsefalqtllsscsrldelnlswcfdftekhv
qvavahvsetitqlnlsgyrknlqksdlstlvrrcpnlvhldlsdsvmlkndcfqeffql
nylqhlslsrcydiipetllelgeiptlktlqvfgivpdgtlqllkealphlqincshft
tiarptignkknqeiwgikcrltlq

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >1fqvP (P:)
mpsiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhk
ddpggsgtddipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpee
irktfnikndfteeeeaqvrkenqwceek

    Sequence, based on observed residues (ATOM records): (download) 
    >1fqvP (P:)
psiklqssdgeifevdveiakqsvtiktmledlgmdpvplpnvnaailkkviqwcthhkd
dipvwdqeflkvdqgtlfelilaanyldikglldvtcktvanmikgktpeeirktfnikn
dfteeeeaqvrkenqwc