PDB entry 1fmo
View 1fmo on RCSB PDB site
Description: crystal structure of a polyhistidine-tagged recombinant catalytic subunit of camp-dependent protein kinase complexed with the peptide inhibitor pki(5-24) and adenosine
Class: complex (phosphotransferase/inhibitor)
Keywords: complex (phosphotransferase/inhibitor), phosphorylation, polyhistidine-tag, protein kinase
Deposited on
1997-07-08, released
1998-01-14
The last revision prior to the SCOPe 2.03 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.182
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'E':
Compound: cAMP-DEPENDENT PROTEIN KINASE
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Uniprot P05132 (Start-349)
- modified residue (196)
- modified residue (337)
Domains in SCOPe 2.03: d1fmoe_ - Chain 'I':
Compound: heat stable rabbit skeletal muscle inhibitor protein
Database cross-references and differences (RAF-indexed):
- Heterogens: ADN, HOH
PDB Chain Sequences:
- Chain 'E':
Sequence, based on SEQRES records: (download)
>1fmoE (E:)
gnaaaakkgseqesvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlv
khkesgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvm
eyvaggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyi
qvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffa
dqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfatt
dwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef
Sequence, based on observed residues (ATOM records): (download)
>1fmoE (E:)
esvkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamk
ildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshl
rrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvk
grtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivs
gkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkvea
pfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef
- Chain 'I':
No sequence available.