PDB entry 1fl7

View 1fl7 on RCSB PDB site
Description: human follicle stimulating hormone
Class: hormone/growth factor
Keywords: cysteine knot, heterodimer
Deposited on 2000-08-11, released 2001-03-14
The last revision prior to the SCOP 1.75 freeze date was dated 2001-03-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.259
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: follicle stimulating protein alpha chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1fl7a_
  • Chain 'B':
    Compound: follicle stimulating protein beta chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01225
      • engineered (25)
    Domains in SCOP 1.75: d1fl7b_
  • Chain 'C':
    Compound: follicle stimulating protein alpha chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1fl7c_
  • Chain 'D':
    Compound: follicle stimulating protein beta chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01225
      • engineered (25)
    Domains in SCOP 1.75: d1fl7d_
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1fl7A (A:)
apdvqdcpectlqenpffsqpgapilqcmgccfsrayptplrskktmlvqknvtsestcc
vaksynrvtvmggfkvenhtachcstcyyhks

    Sequence, based on observed residues (ATOM records): (download) 
    >1fl7A (A:)
qdcpectlqenpffsqpgapilqcmgccfsrayptplrskktmlvqknvtsestccvaks
ynrvtvmggfkvenhtachcstcyyh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1fl7B (B:)
nsceltnitiaiekeecrfcisintawcagycytrdlvykdparpkiqktctfkelvyet
vrvpgcahhadslytypvatqchcgkcdsdstdctvrglgpsycsfgemke

    Sequence, based on observed residues (ATOM records): (download) 
    >1fl7B (B:)
celtnitiaiekeecrfcisintawcagycytrdlvykdparpkiqktctfkelvyetvr
vpgcahhadslytypvatqchcgkcdsdstdctvrglgpsycsfgem

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1fl7C (C:)
apdvqdcpectlqenpffsqpgapilqcmgccfsrayptplrskktmlvqknvtsestcc
vaksynrvtvmggfkvenhtachcstcyyhks

    Sequence, based on observed residues (ATOM records): (download) 
    >1fl7C (C:)
qdcpectlqenpffsqpgapilqcmgccfsrayptplrskktmlvqknvtsestccvaks
ynrvtvmggfkvenhtachcstcyyhks

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1fl7D (D:)
nsceltnitiaiekeecrfcisintawcagycytrdlvykdparpkiqktctfkelvyet
vrvpgcahhadslytypvatqchcgkcdsdstdctvrglgpsycsfgemke

    Sequence, based on observed residues (ATOM records): (download) 
    >1fl7D (D:)
celtnitiaiekeecrfcisintawcagycytrdlvykdparpkiqktctfkelvyetvr
vpgcahhadslytypvatqchcgkcdsdstdctvrglgpsycsfge